1
David Taft, Stelios Tzannis, Wei Guo Dai, Sandra Ottensmann, Steven Bitler, Qiang Zheng, Adam Bell: Method for formulating a controlled-release pharmaceutical formulation. Landec Corporation, James S McDonald, Tim Richardson, March 19, 2013: US08399007 (37 worldwide citation)

Methods for making formulations of drugs and crystalline side chain polymers which formulations provide controlled and/or sustained release drug formulations.


2
Stelios Tzannis, Nancy Dasovich, Sandeep Kumar, Negar Sadrzadeh: Sustained release compositions for delivery of pharmaceutical proteins. Steven J Helmer, March 20, 2007: US07192919 (28 worldwide citation)

The present invention provides sustained release compositions that can be manufactured easily while providing long duration of the pharmaceutically useful protein being delivered. The compositions comprise insoluble complexes of the pharmaceutically useful protein and a precipitating agent at an app ...


3
Pamela Palmer, Andrew Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Lawrence Hamel, William Kolosi, Sascha Retailleau: Methods for administering small volume oral transmucosal dosage forms using a dispensing device. AcelRx Pharmaceuticals, June 17, 2014: US08753308 (20 worldwide citation)

Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in ...


4
Pamela Palmer, Andrew I Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Larry Hamel: Method of moving a delivery member of a dispensing device for administration of oral transmucosal dosage forms. AcelRx Pharmaceuticals, August 6, 2013: US08499966 (10 worldwide citation)

A method of administering small, bioadhesive drug tablets includes moving an end portion of a delivery member. A surface of the delivery member can be positioned to prevent movement of the drug tablet from a tablet cartridge channel to a delivery passage of a delivery device when the end portion of ...


5
Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I Poutiatine, Charles Rampersaud, Bruce Edwards: Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain. AcelRx Pharmaceuticals, July 24, 2012: US08226978 (8 worldwide citation)

Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.


6
Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I Poutiatine, Charles Rampersaud, Bruce Edwards: Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain. AcelRx Pharmaceuticals, Cooley, July 15, 2014: US08778393 (7 worldwide citation)

Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.


7
Stelios Tzannis, Pamela Palmer, Thomas Schreck, Larry Hamel, Andrew I Poutiatine: Bioadhesive drug formulations for oral transmucosal delivery. Acelrx Pharmaceuticals, Cooley, August 28, 2012: US08252328 (6 worldwide citation)

Formulations for controlled delivery of oral transmucosal medications are provided. The formulations are characterized as hydrogel-forming or eroding-types which are bioadhesive and provide for controlled and sustained release of the medication such that enhanced bioavailability and efficacy is prov ...


8
Stelios Tzannis, Larry Hamel, Pamela Palmer, Thomas Schreck, Andrew I Poutiatine: Bioadhesive drug formulations for oral transmucosal delivery. Acelrx Pharmaceuticals, Cooley, August 28, 2012: US08252329 (6 worldwide citation)

Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.


9
Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I Poutiatine: Small-volume oral transmucosal dosage forms. Acelrx Pharmaceuticals, Cooley, June 19, 2012: US08202535 (6 worldwide citation)

Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.


10
Andrew I Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Stelios Tzannis, Pamela Palmer, William Kolosi, Sascha Retailleau: Storage and dispensing devices for administration of oral transmucosal dosage forms. AceIRx Pharmaceuticals, June 30, 2015: US09066847 (5 worldwide citation)

Drug storage and dispensing devices for dispensing dosage forms to the oral mucosa of a patient are disclosed. The drug storage and dispensing device is a single dose applicator or a device which includes a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in ...