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Joanne J Bronson, Stanley V D Andrea, Shelley E Hoeft, John D Matiskella, Peter F Misco Jr, Bing Y Luh, Dane M Springer, Yasutsugu Ueda, John A Wichtowski: Cephalosporin derviatives. Bristol Myers Squibb Company, David M Morse, April 15, 1997: US05620969 (11 worldwide citation)

Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl or pyridyl group; R.sup.1 represents either the residue of a heterocyclic amino acid or a C.sub.2 - ...


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John D Matiskella, Stanley V D Andrea, Thomas W Hudyma, Yasutsugu Ueda, Oak K Kim, Raymond F Miller, Shelley E Hoeft, Joanne J Bronson: Cephalosporin derivatives. Bristol Meyers Squibb Company, David N Morse, July 25, 2000: US06093712 (10 worldwide citation)

Provided are cephem derivatives represented by the general formula ##STR1## wherein Ar, R.sup.1, R.sup.2, R.sup.3, R.sup.9 and R.sup.10 are as defined in the application. The derivatives are gram-positive antibacterial agents especially useful in the treatment of diseases caused by methicillin-resis ...


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Choung U Kim, Muzammil M Mansuri, Peter F Misco Jr, John A Wichtowski, Joanne J Bronson, Stanley V D Andrea, Thomas W Hudyma: Cephalosporin derivatives. Bristol Myers Squibb Company, David M Morse, September 24, 1996: US05559108 (5 worldwide citation)

Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## where Ar is a substituted phenyl or optionally substituted naphthyl or benzthiazolyl group and A is a substituted-pyridinium group are gram-positive antibiotics, espe ...


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Choung U Kim, Peter F Misco Jr, John A Wichtowski, Yasutsugu Ueda, Thomas W Hudyma, John D Matiskella, Stanley V D Andrea, Shelley E Hoeft, Raymond F Miller, Muzammil M Mansuri, Joanne J Bronson: Pyridinium thiomethyl substituted chepholosporin derivatives. Bristol Myers Squibb Company, David M Morse, October 22, 1996: US05567698 (2 worldwide citation)

Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl, pyridyl or benzthiazolyl group; R.sup.1 is selected from certain optionally substituted aliphatic, ...


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Choung U Kim, Peter F Misco Jr, John A Wichtowski, Yasutsugu Ueda, Thomas W Hudyma, John D Matiskella, Stanley V D Andrea, Shelley E Hoeft, Raymond F Miller, Muzammil M Mansuri, Joanne J Bronson: Cephalosporin derivatives. Bristol Myers Squibb Company, David M Morse, September 16, 1997: US05668284

Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl, pyridyl or benzthiazolyl group; R.sup.1 is selected from certain optionally substituted aliphatic, ...


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Joanne J Bronson, Stanley V D Andrea, Shelley E Hoeft, John D Matiskella, Peter F Misco Jr, Bing Yu Luh, Dane M Springer, Yasutsugu Ueda, John A Wichtowski: Substituted 4-thio pyridones. Bristol Myers Squibb Company, David M Morse, September 16, 1997: US05668290

Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl or pyridyl group; R.sup.1 represents either the residue of a heterocyclic amino acid or a C.sub.2 - ...


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Dane M Springer, Bing Y Luh, Stanley V D Andrea, Thomas W Hudyma, Oak K Kim: Cephalosporin derivatives. Marla J Mathias, Bristol Myers Squibb Company, April 25, 2002: US20020049191-A1

The present invention provides a novel series of cephem derivatives of the general formula I 1 wherein R1, R2, R3, R5, R6, R7, A, L1, X, n and n are as defined herein above. The compounds of formula I are antibacterial agents useful in the treatment of infections in humans and other animals caused b ...


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