1
Simon F Williams, David P Martin, Frank A Skraly: Medical devices and applications of polyhydroxyalkanoate polymers. Metabolix, Pabst Patent Group, January 4, 2005: US06838493 (295 worldwide citation)

Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including int ...


2
David P Martin, Frank Skraly, Simon F Williams: Polyhydroxyalkanoate compositions having controlled degradation rates. Metabolix, Pabst Patent Group, March 15, 2005: US06867248 (219 worldwide citation)

Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or include pendant ...


3
Simon F Williams, David P Martin, Frank A Skraly: Medical devices and applications of polyhydroxyalkanoate polymers. Metabolix, Holland & Knight, April 15, 2003: US06548569 (182 worldwide citation)

Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including int ...


4
Simon F Williams, David P Martin, Tillman Gerngross, Daniel M Horowitz: Removing endotoxin with an oxdizing agent from polyhydroxyalkanoates produced by fermentation. Metabolix, Arnall Golden & Gregory, June 12, 2001: US06245537 (127 worldwide citation)

Polyhydroxyalkanoate (PHA) that contains a pyrogen such as endotoxin due to a process of producing the PHA is treated to remove the pyrogen by a process that does not affect the inherent chemical and physical properties of the PHA to obtain a biocompatible PHA. PHA produced by fermentation with a Gr ...


5
Simon F Williams, David P Martin, Frank A Skraly: Medical devices and applications of polyhydroxyalkanoate polymers. Metabolix, Pabst Patent Group, March 15, 2005: US06867247 (103 worldwide citation)

Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including int ...


6
Simon F Williams: Bioabsorbable, biocompatible polymers for tissue engineering. Tepha, Holland & Knight, February 4, 2003: US06514515 (101 worldwide citation)

Bioabsorbable biocompatible polymers which provide a good match between their properties and those of certain tissue structures are provided. The bioabsorbable biocompatible polymers can be prepared with tensile strengths, elongation to breaks, and/or tensile modulus (Young's modulus) values of ...


7
David P Martin, Frank Skraly, Simon F Williams: Polyhydroxyalkanoate compositions having controlled degradation rates. Metabolix, Holland & Knight, August 26, 2003: US06610764 (85 worldwide citation)

Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or include pendant ...


8
David P Martin, Frank Skraly, Simon F Williams: Polyhydroxyalkanoate compositions having controlled degradation rates. Metabolix, Pabst Patent Group, December 7, 2004: US06828357 (81 worldwide citation)

Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or include pendant ...


9
Simon F Williams, David P Martin, Frank A Skraly: Medical devices and applications of polyhydroxyalkanoate polymers. Metabolix, Pabst Patent Group, September 11, 2007: US07268205 (60 worldwide citation)

Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including int ...


10
David P Martin, Frank Skraly, Simon F Williams: Polyhydroxyalkanoate compositions having controlled degradation rates. Metabolix, Pabst Patent Group, April 12, 2005: US06878758 (47 worldwide citation)

Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or include pendant ...