1
Shunji Kasai, Toshihiro Akaike, Teruo Miyata: Substratum for cell culture and a method for culturing and isolating cells using same. Koken, Armstrong Nikaido Marmelstein & Kubovcik, December 17, 1985: US04559304 (39 worldwide citation)

A substratum for cell culture which comprises a chemically modified collagen rich in either positive or negative charges when under culture conditions. The substratum is prepared by modifying the amino groups or carboxyl groups of collagen. The chemically modified collagen enhances the adherence and ...


2
Masanobu Shinoda, Eita Emori, Fumiyoshi Matsuura, Toshihiko Kaneko, Norihito Ohi, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Sadakazu Miyashita, Taro Hibara, Takashi Seiki, Richard Clark, Hitoshi Harada: Carboxylic acid derivatives and drugs containing the same. Eisai, Birch Stewart Kolasch & Birch, April 26, 2005: US06884821 (23 worldwide citation)

Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, R1 is hydrogen, hydroxyl, alkyl, or the like; L is a sin ...


3
Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Richard Clark, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara: Benzene compound and salt thereof. Eisai, Birch Stewart Kolasch & Birch, July 17, 2007: US07244861 (11 worldwide citation)

The present invention provides a medicament comprising a benzene compound useful as an insulin sensitizer, a salt thereof or a hydrate of them and a derivative of them as the active ingredient. Specifically, it provides a benzene compound represented by the following formula, a salt thereof or a hyd ...


4
Richard Clark, Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara: Cyclic compound and PPAR agonist. Eisai, Birch Stewart Kolasch & Birch, May 13, 2008: US07371777 (5 worldwide citation)

The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each re ...


5
Shunji Kasai, Ryuji Hiramatsu, Shusei Uno, Masanori Nagai, Hirofumi Arimura, Toshizumi Tanabe, Yasuo Amatsuji, Masaaki Hirose, Masanori Morita, Haruhide Kawabe: Human prourokinase mutants. The Green Cross Corporation, Sughrue Mion Zinn Macpeack & Seas, March 24, 1992: US05098840 (4 worldwide citation)

A human prourokinase mutant in which the entire or a partial epidermal growth factor domain of human prourokinase is deleted or a partial epidermal growth factor domain of human prourokinase is replaced by one or more different amino acid residues, said mutant having a longer blood half-life than na ...


6
Hitoshi Harada, Masanobu Shinoda, Richard Clark, Fumiyoshi Matsuura, Eita Emori, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara: Carboxylic acids. Eisai, Birch Stewart Kolasch & Birch, August 7, 2007: US07253178 (3 worldwide citation)

The present invention provides a novel carboxylic acid derivative, a salt thereof or a hydrate of them which is useful as an insulin sensitizer, and a medicament comprising the derivative as the effective ingredient. More specifically, it provides a carboxylic acid compound represented by the formul ...


7
Hiroyuki Yoshimoto, Yasuhiko Sawada, Shunji Kasai, Shuji Tagashira: Molded object process for producing the same product for high-frequency signal transmission and high-frequency transmission cable. Daikin, Birch Stewart Kolasch & Birch, June 8, 2010: US07732531 (1 worldwide citation)

The present invention provides a molded article comprising a polytetrafluoroethylene resin (A) and a thermoplastic resin (B) having a melting point of not lower than 100° C. but lower than 322° C., wherein the maximum peak temperature of the endothermic curve appearing on the crystal melting curve o ...


8
Fumiyoshi Matsuura, Eita Emori, Masanobu Shinoda, Richard Clark, Shunji Kasai, Hideki Yoshitomi, Kazuto Yamazaki, Takashi Inoue, Sadakazu Miyashita, Taro Hihara, Hitoshi Harada, Kaya Ohashi: Carboxylic acid derivative and salt thereof. Eisai R&D Management, Birch Stewart Kolasch & Birch, June 9, 2009: US07544835 (1 worldwide citation)

Carboxylic acid compound or salt or hydrate thereof useful as insulin sensitizer, represented by the formula wherein R1 represents hydrogen, hydroxyl, halogen, carboxyl, or C1-6 alkyl, L represents single bond or C1-6-alkylene, C2-6-alkenylene, or C2-6-alkynylene, M represents single bond or C1-6-al ...


9
Kunihiko Inui, Yoshiyuki Shibuya, Shunji Kasai, Taku Yamanaka: Filter medium equipped with porous film, method of manufacturing same, filter pack, and filter unit. Daikin, Global IP Counselors, July 7, 2015: US09072993 (1 worldwide citation)

A filter medium includes a porous film and a support material supporting the porous film. The porous film includes polytetrafluoroethylene, has an average pore diameter of at least 2.5 μm, and has a porosity of at least 95%. A pressure loss is less than 100 Pa when air is passed through the filter m ...


10
Shinichi Chaen, Hideyuki Kiyotani, Kunihiko Inui, Taku Yamanaka, Li Bao, Yoshiyuki Shibuya, Seigo Yamamoto, Makoto Kobayashi, Shunji Kasai, Hitoshi Niinuma: Composition having PTFE as main component, mixed powder, material for molding, filtering medium for filter, air filter unit, and a method for manufacturing a porous membrane. Daikin, Global IP Counselors, July 18, 2017: US09707504 (1 worldwide citation)

A composition, a mixed powder and a material for molding have polytetrafluoroethylene as a main component. Each includes polytetrafluoroethylene that can be fibrillated, a non-hot melt processable component that is not fibrillated, and a hot melt processable component with a melting point of lower t ...