1
Shuichiro Yamaguchi, Naoto Uchida, Takeshi Shimomura, Noboru Oyama: Enzyme sensor. Terumo Kabushiki Kaisha, Burns Doane Swecker & Mathis, May 22, 1990: US04927516 (504 worldwide citation)

Disclosed is an enzyme sensor for measuring a predetermined substrate concentration by potentiometric or amperometric response on the basis of an enzyme. In one aspect, a solid-state enzyme sensor measures a predetermined substrate concentration by potentiometric response and includes a solid enzyme ...


2
Noboru Oyama, Takeshi Shimomura, Shuichiro Yamaguchi: Enzyme sensor and method of manufacturing the same. Burns Doane Swecker & Mathis, April 27, 1993: US05205920 (386 worldwide citation)

An enzyme sensor is disclosed, which has a two-layer fixed film structure consisting of a reduction function layer including an electron movement medium and di-valent iron ions and an enzyme-fixed layer covering said reduction function layer, and in which hydrogen peroxide generated through decompos ...


3
Shuichiro Yamaguchi, Norihiko Ushizawa, Takeshi Shimomura, Noboru Oyama: Ion sensor. Terumo Kabushiki Kaisha, Cushman Darby & Cushman, July 28, 1992: US05133856 (254 worldwide citation)

An ion sensor of the type wherein a specific type of ion in an aqueous solution is measured by potential response. The sensor includes a conductor base, and a reversible redox polymer film formed directly on a surface of said conductor base. An ion carrier film is formed directly on a surface of sai ...


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Teruaki Katsube, Shuichiro Yamaguchi, Naoto Uchida, Takeshi Shimomura: Apparatus for forming thin film. Teruaki Katsube, Terumo Kabushiki Kaisha, Burns Doane Swecker & Mathis, March 22, 1994: US05296122 (45 worldwide citation)

In the manufacture of a substrate with a hydrophobic film used for a reference electrode of an ion sensor or the like, a hydrophobic film is formed on a substrate by irradiating a target consisting of a hydrophobic compound with a neutral atom beam and thereby effecting sputtering. The apparatus for ...


6
Shuichiro Yamaguchi, Norihiko Ushizawa, Norio Daikuhara, Takeshi Shimomura, Naoto Uchida: Biological information measurement apparatus. Terumo Kabushiki Kaisha, Burns Doane Swecker & Mathis, June 30, 1992: US05126937 (29 worldwide citation)

A biological information measurement apparatus is adapted to measure biological information in an extracorporeal circuration or in a living body by various measurement circuits comprising circuit elements which are not affected by electrical disturbances, and to transmit the results of measurement i ...


7
Noboru Oyama, Takeshi Shimomura, Shuichiro Yamaguchi: Ion-sensitive FET sensor. Terumo Corporation, Burns Doane Swecker & Mathis, March 28, 1989: US04816118 (26 worldwide citation)

An ion-sensitive FET sensor has a MOSFET gate isolating membrane whose surface is covered by an ion-sensitive layer. A redox layer having a redox function is provided between the isolating membrane and the ion-sensitive layer to improve operating stability and speed of response. An electrically cond ...


8
Noboru Oyama, Shuichiro Yamaguchi, Takeshi Shimomura, Keizaburo Miki: Method for detecting target sequences by oscillation frequency. Terumo Kabushiki Kaisha, Burns Doane Swecker & Mathis, September 3, 1996: US05552274 (23 worldwide citation)

Methods for detecting target DNA's in a sample on the basis of oscillation frequency using nucleic acid sequences immobilized to the surface of an electrode of an elastic wave element, and DNA sensors for conducting the methods are described. These methods provide for highly sensitive detection of t ...


9
Shuichiro Yamaguchi, Norio Daikuhara, Takeshi Shimomura: Gas sensor. Terumo Kabushiki Kaisha, Burns Doane Swecker & Mathis, June 13, 1989: US04839020 (22 worldwide citation)

A gas sensor includes a multi-layered solid-state pH electrode and a reference electrode coated with a gas-sensitive layer (solid-state or gel-state) sensitive to an ion of interest, the surface of the combination being coated with a gas-permable layer. Also provided in a gas sensor having a pH elec ...


10
Takeshi Shimomura, Shuichiro Yamaguchi, Norihiko Ushizawa, Noboru Oyama: Reference electrode. Terumo Kabushiki Kaisha, Frishauf Holtz Goodman & Woodward, March 26, 1985: US04507194 (17 worldwide citation)

A reference electrode is prepared by coating the surface of a conductive substrate with a silver complex polymer compound, which is either a compound prepared by the complex formation between a polymer compound containing a coordination nitrogen atom and a silver ion or an aforementioned complex com ...



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