1
Masanori Oka, Shokyu Gen, Yoshito Ikada, Hideaki Okimatsu: Artificial intervertebral disc. Kyocera Corporation, Kabushiki Kaisha Biomaterial Universe Corporation of Japan, Spensley Horn Jubas & Lubitz, October 17, 1995: US05458643 (467 worldwide citation)

A prosthesis used for a damaged bone, an artificial articular cartilage or an artificial intervertebral disc being characterized in that the prosthesis is a composite body comprising polyvinyl alcohol hydrogel and ceramic or metallic porous body. With this prosthesis, PVA hydrogel enhances lubricati ...


2
Masanori Oka, Shokyu Gen, Yoshito Ikada, Hideaki Okimatsu: Artificial bone connection prosthesis. Kyocera Corporation, Kabushiki Kaisha Biomaterial Universe, Spensley Horn Jubas & Lubitz, May 24, 1994: US05314478 (290 worldwide citation)

A prosthesis used for a damaged bone, an artificial articular cartilage or an artificial intervertebral disc being characterized in that the prosthesis is a composite body comprising polyvinyl alcohol hydrogel and ceramic or metallic porous body. With this prosthesis, PVA hydrogel enhances lubricati ...


3
Yoshito Ikada, Shokyu Gen, Yasuhiko Shimizu, Koichi Tamura, Tatsuo Nakamura, Sosuke Kimura, Tsuneo Cho, Hideki Tadokoro, Kazuaki Hori: Use of molded polymeric material for preventing adhesion of vital tissues. Japan Medical Supply, Kramer and Brufsky, August 5, 1986: US04603695 (59 worldwide citation)

An adhesion preventive for preventing adhesion between vital tissues is provided. The present adhesion preventive is a molded material consisting essentially of a biodegradable and absorbable polymer. It has an advantage of requiring no reoperation for its removal since it would be degraded and abso ...


4
Yoshito Ikada, Shokyu Gen, Tatsuya Kawai, Takashi Matsuda: Sucrose fatty acid ester coated suture. Japan Medical Supply, Gunze, Bio Materials Universe, Kramer Brufsky & Cifelli, July 4, 1989: US04844067 (55 worldwide citation)

A suture coating composition comprising a sucrose fatty acid ester and sutures coated therewith whereby said sutures exhibit improved smoothness in tie-down properties and knotting can be readily accomplished using said suture.


5
Yoshito Ikada, Shokyu Gen, Shigeo Ohi, Yosuke Urabe, Hiroyuki Kawashima: Artificial skin. Dow Corning Kabushiki Kaisha, Allan O Maki, November 21, 1989: US04882162 (53 worldwide citation)

An artificial skin or bandage is formed from an elastomeric layer which is surfaced by a fibrous wound contacting layer which is first formed into a fabric and subsequently degraded by heat hydrolysis or other degradative treatment into a form which could no longer be formed into a fabric but which ...


6
Yoshito Ikada, Shokyu Gen: Periodontium-regenerative materials. G C Dental Industrial, Oblon Spivak McClelland Maier & Neustadt, October 5, 1993: US05250584 (43 worldwide citation)

A periodontium-regenerating material for the regenerative treatment of the periodontium consists of bio-degradable/absorable copolymers of lactide/.epsilon.-caprolactone or lactide/glycolide having a weight-average molecular weight of 40,000 to 500,000 as well as a dynamic modulus of 5.times.10.sup. ...


7
Yoshito Ikada, Shokyu Gen: Process for producing a low water content PVA hydrogel. Dow Corning, Bio Materials Univers Co, Kyocera, Allen O Maki, January 29, 1991: US04988761 (37 worldwide citation)

The present invention relates to a method of producing polyvinyl alcohol hydrogel characterized by the following features: the production process consists of a low-temperature processing stage in which the solution of polyvinyl alcohol with a polymerization degree over 1200 is processed at a low tem ...


8
Shozo Muranishi, Yoshito Ikada, Hiroshi Yoshikawa, Shokyu Gen: Polylactic acid microspheres and process for producing the same. Sanraku Incorporated, Biomaterials Universe Incorporated, Jordan and Hamburg, February 19, 1991: US04994281 (36 worldwide citation)

Polylactic acid microspheres having an average particle diameter of about 0.1 to 10 .mu.m which are produced from solution containing a physiologically active substance by the solvent-evaporation drying process. The microspheres are produced by emulsifying the solution in a non-solvent by the aid of ...


9
Yoshito Ikada, Shokyu Gen: Polylactic acid fiber. Daicel Chemical, Flynn Thiel Boutell & Tanis, April 23, 1991: US05010145 (22 worldwide citation)

A polylactic acid fiber comprises a blend of poly-L-lactic acid and poly-D-lactic acid and is improved by spinning and then drawing.


10
Shokyu Gen: Bio-decomposable polymer composition showing good thermal decomposition. BMG Incorporated, Jordan and Hamburg, September 27, 2005: US06949254 (9 worldwide citation)

A biodegradable polymer composition having good resistance to thermal decomposition, wherein it is possible to control the weight-average molecular weight to within 30% of the initial molecular weight after molding and radiation sterilization, by adding a free radical scavenger to the biodegradable ...