1
Sean Selover, Sara Dziedzic, Steve Connolly, Sheryl Frank, Lorenzo Vaccarella: Illuminated surgical access system including a surgical access device and coupled light emitter. DePuy Spine, Lahive & Cockfield, Kevin J Canning, EuiHoon Lee, January 25, 2011: US07874982 (19 worldwide citation)

A surgical access system for providing access to a surgical site in a patient includes a surgical access device defining a port and a light emitter coupled to the surgical access device for illuminating the port. The light emitter preferably comprises an elongated shaft having a light transmitting e ...


2
Jeffrey Shuster, Matthew M Tanzer, Lisbeth Hamer, Kiichi Adachi, Todd M DeZwaan, Sze Chung Lo, Maria Victoria Montenegro Chamorro, Blaise Darveaux, Sheryl Frank, Ryan Heiniger, Sanjoy K Mahanty, Huaqin Pan, Amy Skalchunes, Rex W Tarpey: Methods for the identification of inhibitors of homocitrate synthase as antibiotics. Paradigm Genetics, Deborah H Spencer, Timothy G Hofmeyer, Laura L Kiefer, October 14, 2003: US06632631 (12 worldwide citation)

The present inventors have discovered that homocitrate synthase is essential for fungal pathogenicity. Specifically, the inhibition of homocitrate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, homocitrate synthase can be used as a target for the iden ...


3
Todd DeZwaan, Sze Chung Lo, Maria Victoria Montenegro Chamarro, Sheryl Frank, Blaise Darveaux, Sanjoy K Mahanty, Ryan Heiniger, Amy Skalchunes, Huaqin Pan, Rex Tarpey, Jeffrey Shuster, Matthew M Tanzer, Lisbeth Hamer, Kiichi Adachi: Methods for the identification of inhibitors of 5-aminolevulinate synthase as antibiotics. Paradigm Genetics, Laura L Kiefer, Timothy G Hofmeyer, Deborah H Spencer, February 10, 2004: US06689578 (5 worldwide citation)

The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, 5-Aminolevulinate synthase can be used as a t ...


4
Nicholas Pavento, John Riley Hawkins, Sheryl Frank, Douglas Raymond: Nubbed plate. DePuy Synthes Products, Raymond N Scott Jr, March 1, 2016: US09271836 (3 worldwide citation)

A separate nub component between the plate and an intervertebral fusion cage, wherein the nub is attached to the plate. The nub lessens the undesired pivotal movement of the plate. It is believed that when the nub fits snugly between the endplates of the adjacent vertebral bodies, it acts as a stop ...


5
Maria Victoria Montenegro Chamorro, Sheryl Frank, Blaise Darveaux, Sanjoy Mahanty, Ryan Heiniger, Amy Skalchunes, Huaqin Pan, Rex Tarpey, Jeffrey Shuster, Matthew M Tanzer, Lisbeth Hamer, Kiichi Adachi, Todd DeZwaan, Sze Chung Lo: Methods for the identification of inhibitors of threonine synthase as antibiotics. Icoria, Laura L Kiefer, Timothy G Hofmeyer, Deborah H Spencer, October 19, 2004: US06806060 (1 worldwide citation)

The present inventors have discovered that Threonine synthase is essential for fungal pathogenicity. Specifically, the inhibition of Threonine synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, Threonine synthase can be used as a target for the identifica ...


6
Michael J O Neil, Jonathan Bellas, Cody Cranson, Sheryl Frank, Michael Toto: Universal trial for lateral cages. DePuy Synthes Products, March 14, 2017: US09592063

A method of trialing an intervertebral disc space, including the steps of creating the disc space, inserting a trial into the disc space, wherein the trial has i) a distal head having an upper surface and a lower surface connected by a pair of side walls, the side walls defining planes, and ii) a pr ...


7
Sean Selover, Sara Dziedzic, Steve Connolly, Sheryl Frank, Lorenzo Vaccarella: Illuminated surgical access system including a surgical access device and coupled light emitter. Depuy Synthes Products, Nelson Mullins Riley & Scarborough, April 14, 2015: US09005118

A surgical access system for providing access to a surgical site in a patient includes a surgical access device defining a port and a light emitter coupled to the surgical access device for illuminating the port. The light emitter preferably comprises an elongated shaft having a light transmitting e ...


8
Sze Chung Lo, Maria Victoria Montenegro Chamorro, Sheryl Frank, Blaise Darveaux, Sanjoy Mahanty, Ryan Heiniger, Amy Skalchunes, Huaqin Pan, Rex Tarper, Jeffrey Shuster, Matthew M Tanzer, Lisbeth Hamer, Kiichi Adachi, Todd M DeZwaan: Methods for the identification of inhibitors of asparagine synthase as antibiotics. Icoria, Laura L Kiefer, Timothy G Hofmeyer, Deborah H Spencer, February 8, 2005: US06852484

The present inventors have discovered that Asparagine Synthase is essential for fungal pathogenicity. Specifically, the inhibition of Asparagine Synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, Asparagine Synthase can be used as a target for the identif ...


9
Matthew M Tanzer, Jeffrey Shuster, Lisbeth Hamer, Kiichi Adachi, Todd M DeZwaan, Sze Chung Lo, Maria Victoria Montenegro Chamorro, Sheryl Frank, Blaise Darveaux, Sanjoy K Mahanty, Ryan Heiniger, Amy Skalchunes, Huaqin Pan, Rex Tarpey: Methods for the identification of inhibitors of &agr;-aminoadipate reductase as antibiotics. Paradigm Genetics, Deborah H Spencer, Timothy G Hofmeyer, Laura L Kiefer, April 20, 2004: US06723529

The present inventors have discovered that &agr;-Aminoadipate Reductase is essential for fungal pathogenicity. Specifically, the inhibition of &agr;-Aminoadipate Reductase gene expression in fungi results in no signs of successful infection or lesions. Thus, &agr;-Aminoadipate Reductase can be used ...


10
Blaise Darveaux, Sanjoy Mahanty, Ryan Heiniger, Amy Covington, Huaqin Pan, Rex Tarpey, Jeffrey Shuster, Matthew M Tanzer, Lisbeth Hamer, Kiichi Adachi, Todd DeZwaan, Sze Chung Lo, Maria Victoria Montenegro Chamorro, Sheryl Frank: Methods for the identification of inhibitors of Trehalose-6-Phosphate Synthase as antibiotics. Paradigm Genetics, July 29, 2004: US20040146960-A1

The present inventors have discovered that Trehalose-6-Phosphate Synthase is essential for normal fungal pathogenicity. Specifically, the inhibition of Trehalose-6-Phosphate Synthase gene expression in fungi results in reduced pathogenicity (i.e. smaller, non-viable lesions). Thus, Trehalose-6-Phosp ...