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Shazia Sadiq, Wasim Sadiq, Maria E Orlowska: System and method of flexible workflow management. SAP Aktiengesellschaft, Fish & Richardson P C, February 8, 2011: US07885840 (17 worldwide citation)

A flexible workflow is described that includes a pocket of flexibility. The pocket of flexibility may include workflow fragments that may be joined together, subject to pre-defined constraints. In implementing the flexible workflow, a user may encounter the pocket of flexibility, and select from the ...


2
Guy Brenchley, Steven Durrant, Jean Damien Charrier, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq: Thiophene-carboxamides useful as inhibitors of protein kinases. Lisa A Dixon, Booyong S Lim, November 9, 2010: US07829590 (8 worldwide citation)

The present invention relates to compounds useful as inhibitors of protein kinase, represented by structural formula I: or pharmaceutically acceptable salts thereof, wherein values of the variables of structural formula are as described in the specification and claims. The invention also provides ph ...


3
Guy Brenchley, Steven Durrant, Jean Damien Charrier, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq: Thiophene-carboxamides useful as inhibitors of protein kinases. Vertex Pharmaceuticals Incorporated, Rory C Stewart, May 29, 2012: US08188134 (8 worldwide citation)

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also pro ...


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Saleh Ahmed, Oscar Barba, Jason Bloxham, Graham Dawson, William Gattrell, John Kitchin, Neil Anthony Pegg, Imaad Saba, Shazia Sadiq, Colin Peter Sambrook Smith, Don Smyth, Amo G Steinig, Robin Wilkes, Bijoy Panicker, Paula Tavares, Matthew Cox, An Hu Li, Hanqing Dong, Lifu Ma, Kenneth, Qinghua, Kathryn Stolz: Substituted pyrrolo[2.3-B]pyridines. OSI Pharmaceuticals, December 16, 2008: US07465726 (4 worldwide citation)

Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, Mek1, PDK-1, GSK3β, EGFR, p70S6K, BMX, SGK, CaMKII, Tie-2, IGF-1R, Ron, Ret, and KDR kinases in animal ...


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Guy Brenchley, Jean Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq, Jingrong Cao: Azaindazoles useful as inhibitors of kinases. Vertex Pharmaceuticals Incorporated, Rocy C Stewart, September 13, 2011: US08017781 (2 worldwide citation)

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also pr ...


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Jason Bloxham, Gary V Borzillo, Eric William Collington, Shazia Sadiq, Colin Peter Sambrook Smith, Chris L Waller, Graham M Wynne: Integrin antagonists useful as anticancer agents. OSI Pharmaceuticals, Michael J Rafa, OSI Pharmaceuticals, August 23, 2011: US08003806 (2 worldwide citation)

The invention relates to compounds of the Formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X2, X4, X5 and X1 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of Formula 1 and to ...


8
Guy Brenchley, Jean Damien Charrier, Steven Durrant, David Kay, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq: Thiophene-carboxamides useful as inhibitors of protein kinases. Vertex Pharmaceuticals Incorporated, Booyong S Lim, Lisa A Dixon, March 29, 2011: US07915305

The present invention relates to compounds useful as inhibitors of protein kinase represented by formula (I): or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the tre ...


9
Guy Brenchley, Jean Damien Charrier, Steven Durrant, David Kay, Ronald Knegiel, Sharn Ramaya, Shazia Sadiq: Thiophene-carboxamides useful as inhibitors of protein kinases. Vertex Pharmaceuticals Incorporated, Rory C Stewart, March 19, 2013: US08399478

The present invention relates to compounds useful as inhibitors of protein kinase represented by formula (I): or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the tre ...


10
Guy Brenchley, Jean Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq: Thiophene-carboxamides useful as inhibitors of protein kinases. Vertex Pharmaceuticals Incorporated, Rory C Stewart, October 18, 2011: US08039661

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The i ...