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Donna L Romero, Matthew David Wessel, Shaughnessy Robinson, Jeremy Robert Greenwood, Karl Shawn Watts, Leah Lynn Frye, Geraldine C Harriman, Alan Franklin Corin, Craig E Masse, Mee Shelley: IRAK inhibitors and uses thereof. Nimbus Iris, Choate Hall & Stewart, Andrea C Robidoux, Thomas H McLean, April 22, 2014: US08703941 (8 worldwide citation)

The present invention provides thienopyrimidine and thienopyridine compounds, compositions thereof, and methods of using the same for the treatment of diseases mediated by IRAK enzymes. Such diseases include inflammatory and proliferative diseases.


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Carl R Illig, Eugene R Cooper, John L Toner, Donald A Upson, Brent D Douty, Thomas J Caulfield, Bacon Edward R, Kimberly G Estep, Kurt A Josef, Shaughnessy Robinson, Paul P Spara: Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract. Sterling Winthrop, Arthur Rosenstein, Imre Balogh, July 5, 1994: US05326553 (7 worldwide citation)

Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1## and methods for their use in diagnostic radiology ...


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Baldev Singh, Edward R Bacon, Shaughnessy Robinson: Iodinated aroyloxy ketones. Eastman Kodak Company, Arthur H Rosenstein, January 30, 1996: US05488133 (3 worldwide citation)

Compounds having the structure ##STR1## wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 20;


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Donna L Romero, Shaughnessy Robinson, Matthew David Wessel, Jeremy Robert Greenwood: IRAK inhibitors and uses thereof. Nimbus Iris, Choate Hall & Stewart, Andrea L C Reid, Thomas H McLean, July 21, 2015: US09085586 (2 worldwide citation)

The present invention provides arylo-fused thienopyrimidine compounds, compositions thereof, and methods of using the same.


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Donna L Romero, Matthew David Wessel, Shaughnessy Robinson, Jeremy Robert Greenwood, Karl Shawn Watts, Leah Lynn Frye, Geraldine C Harriman, Alan Franklin Corin, Craig E Masse, Mee Shelley: IRAK inhibitors and uses thereof. NIMBUS IRIS, Dechert, Andrea L C Reid, May 17, 2016: US09340554 (1 worldwide citation)

The present invention provides 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine compounds and pharmaceutical compositions thereof as inhibitors of IRAK.


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Donna Romero, Craig E Masse, Shaughnessy Robinson, Jeremy Robert Greenwood, Geraldine C Harriman: IRAK inhibitors and uses thereof. Nimbus Iris, Andrea L C Reid, Dechert, December 13, 2016: US09518065

The present invention provides compounds of the general formula I: or a pharmaceutically acceptable salt thereof, wherein each variable is as defined and described herein, as inhibitors of one or more interleukin-1 receptor-associated kinases (“IRAK”).