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Sun Lihong, Niu Deqiang, Shan Feng, Lee Wen Cherng, Feng Xiaomei: Spiro compounds as antagonists of tgf-beta. Biogen Idec Ma, Sun Lihong, Niu Deqiang, Shan Feng, Lee Wen Cherng, Feng Xiaomei, O BRIEN Jonathan P, January 15, 2009: WO/2009/009059 (29 worldwide citation)

The invention is related to compounds of formula (I) These compounds can be used as antagonists of the TGF-beta family tyle I receptors, Alk5 or Alk4. The compounds of formula (I) can be employed in the prevention and/or treatment of diseases such as fibrosis (e. g. renal fibrosis, pulmonary fibrosi ...


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Lee Wen Cherng, Sun Lihong, Shan Feng, Chuaqui Claudio, Cornebise Mark, Pontz Timothy W, Carter Marybeth, Singh Juswinder, Boriack Sjodin Paula Ann, Ling Leona, Petter Russell C: Pyrazoles and methods of making and using the same. Biogen Idec Ma, Lee Wen Cherng, Sun Lihong, Shan Feng, Chuaqui Claudio, Cornebise Mark, Pontz Timothy W, Carter Marybeth, Singh Juswinder, Boriack Sjodin Paula Ann, Ling Leona, Petter Russell C, LINKKILA Timothy P, August 26, 2004: WO/2004/072033 (18 worldwide citation)

The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound ...


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Lee Wen Cherng, Sun Lihong, Chuaqui Claudio, Cornebise Mark, Singh Juswinder, Shan Feng: Pyrimidinylpyrazoles as tgf-beta inhibitors. Biogen Idec Ma, Lee Wen Cherng, Sun Lihong, Chuaqui Claudio, Cornebise Mark, Singh Juswinder, Shan Feng, O BRIEN Jonathan P, March 9, 2006: WO/2006/026305 (13 worldwide citation)

The invention is based on the discovery that compounds of formula (I) possess high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. The invention features a compound of formula (I) and uses there ...


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Chun Wen Wang, Shan Feng Chang: Dual-axis hinge structure and electric device having the same. Quanta Computer, Rabin & Berdo P C, February 26, 2013: US08385991 (7 worldwide citation)

A dual-axis hinge structure and electric device having the same are provided, and the dual-axis hinge structure includes a hinge base having a pushed portion, a first pivot portion having a first cam and a first shaft, a second pivot portion having a second cam and a second shaft, and a restoring me ...


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Lee Wen Cherng, Sun Lihong, Chuaqui Claudio, Singh Juswinder, Shan Feng: Pyrimidinylimidazoles as tgf-beta inhibitors. Biogen Idec Ma, Lee Wen Cherng, Sun Lihong, Chuaqui Claudio, Singh Juswinder, Shan Feng, O BRIEN Jonathan P, March 9, 2006: WO/2006/026306 (5 worldwide citation)

Compounds of formula (I) possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. The invention features a compound of the general formula (I) and uses thereof.


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Jeffrey Allen Apgar, Karthikeyan Govindhasamy, Shan Feng Chang, John Hwang: Flexible hinge for electronic devices. Nokia Corporation, Harrington & Smith, May 14, 2013: US08438702 (4 worldwide citation)

In accordance with an example embodiment of the present invention, an apparatus comprises a flexible hinge comprising first and second layers; the first layer comprising an elastomer and the second layer comprising a composite fabric.


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Shan Feng: Piano learning guidance system. May 16, 2017: US09652994 (2 worldwide citation)

Disclosed is a piano learning guidance system, comprising a piano and two hand drums, wherein the piano comprises a control module, a storage module, a first LCD display screen, a second LCD display screen, a third LCD display screen, a key recording microphone and a plurality of first LED light bar ...


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Shan Feng Lien: Rotary and rocking toy device. Alan Oppenheimer Wolff & Donnelly Kamrath, September 21, 1999: US05954588 (2 worldwide citation)

A rotary and rocking toy device has four bottom seats, four roller wheels, four support frames, and four carriers. The support frames are connected together to form a cross shape. Each roller wheel is disposed on the respective bottom seat. Each support frame is connected to the respective roller wh ...


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Shan Feng: Electric violin. December 29, 2015: US09224376 (1 worldwide citation)

An electric violin comprises a head, a body and a bowstring module; the head is attached to the body via a connecting rod. The head includes a display screen and several string-buttons mounted at a side of the display screen. Each string-button is corresponding in position with one line of string-re ...


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