1
John I Peterson, Seth R Goldstein: Fiber optic pH probe. United States of America, Holman & Stern, April 29, 1980: US04200110 (288 worldwide citation)

A fiber optic pH probe suitable to be implanted in tissue for physiological studies is disclosed. The probe includes an ion permeable membrane envelope which encloses the ends of a pair of optical fibers. A pH sensitive dye indicator composition is present within the envelope. The probe operates on ...


2
Seth R Goldstein: Confocal scanning laser microscope having no moving parts. The United States of America represented by the Secretary of the Department of Health and Human Services, Holman & Stern, May 2, 1989: US04827125 (88 worldwide citation)

A confocal scanning laser microscope has no moving parts and displays real time video images. The image of the scanned laser spot on the specimen is focused on the photocathode of an image dissector tube having an electron image deflection that is synchronized and aligned with the laser scan. This p ...


3
Seth R Goldstein, Robert Jones: Method and apparatus for traversing blood vessels. The United States of America represented by the Department of Health and Human Services, Holman & Stern, July 23, 1985: US04530698 (52 worldwide citation)

Disclosed is a method for obtaining access to a relatively inaccessible region of a blood vessel for diagnostic or therapeutic purposes in which a primary catheter tube is inserted into the vascular system at an entry point remote from the relatively inaccessible region, the leading end of the tube ...


4
Seth R Goldstein: Magnetic fluid actuated control valve, relief valve and pump. The United States of America represented by the Secretary of the Department of Health Education and Welfare, Browdy and Neimark, October 18, 1977: US04053952 (49 worldwide citation)

An electrically controlled magnetic fluid actuated device, which can be used in controlling fluid flow and which has particular utility in controlling this flow from a pressurized reservoir implanted in the body such as might be used for an artificial pancreas, sphincter for bladder control or other ...


5
Robert F Bonner, Lance A Liotta, Michael Emmert Buck, David B Krizman, Rodrigo Chuaqui, W Marston Linehan, Jeffry M Trent, Seth R Goldstein, Paul D Smith, John I Peterson: Isolation of cellular material under microscopic visualization. The United States of America represented by the Department of Health and Human Services, Townsend and Townsend and Crew, June 26, 2001: US06251516 (22 worldwide citation)

A method of microdissection which involves forming an image field of cells of the tissue sample utilizing a microscope, identifying at least one zone of cells of interest from the image field of cells which at least one zone of cells of interest includes different types of cells than adjacent zones ...


6
Lance A Liotta, Michael Emmert Buck, David B Krizman, Rodrigo Chuaqui, W Marston Linehan, Jeffry M Trent, Robert F Bonner, Seth R Goldstein, Paul D Smith, John I Peterson: Isolation of cellular material under microscopic visualization. The United States of America represented by the Department of Health and Human Services, Townsend and Townsend and Crew, June 26, 2001: US06251467 (19 worldwide citation)

A method of microdissection which involves forming an image field of cells of the tissue sample utilizing a microscope, identifying at least one zone of cells of interest from the image field of cells which at least one zone of cells of interest includes different types of cells than adjacent zones ...


7
Seth R Goldstein, Robert F Bonner, Paul D Smith, John Peterson, Thomas Pohida: Method utilizing convex geometry for laser capture microdissection. The United States of America represented by the Department of Health and Human Services, Townsend and Townsend and Crew, August 8, 2000: US06100051 (16 worldwide citation)

A process of microdissection where a tissue sample is conventionally visualized in a microscope. A selectively activatable convex surface is provided, preferably on the periphery at the distal end of a rod. This selectively activatable convex surface when locally activated, typically with a laser th ...


8
Seth R Goldstein, Robert F Bonner, Paul D Smith, John Peterson, Thomas Pohida: Mechanical handling systems for laser capture microdissection. The United States of America represented by the Department of Health and Human Services, William Michael Hynes, Townsend and Townsend and Crew, April 13, 2004: US06720191 (9 worldwide citation)

A method and apparatus of gathering by LCM identified cellular material from randorn locations on a tissue sample to designated locations on a transporting substrate enables convenient further processing. A transporting substrate has an identified mapped location for receiving identified cellular ma ...


9
Robert F Bonner, Seth R Goldstein, Paul D Smith, Thomas Pohida: Non-contact laser capture microdissection. The United States of America represented by the Department of Health and Human Services, William Michael Hynes, Townsend and Townsend and Crew, June 1, 2004: US06743601 (8 worldwide citation)

An apparatus and process for the micro juxtaposition is set forth where a selectively activatable surface is maintained spaced apart from the tissue sample and juxtaposed to the tissue sample by activation. In the typical case, activation occurs by laser radiation with the material of the activatabl ...


10
Lance A Liotta, Michael Emmert Buck, David B Krizman, Rodrigo Chuaqui, W Marston Linehan, Jeffry M Trent, Robert F Bonner, Seth R Goldstein, Paul D Smith, John I Peterson: Isolation of cellular material under microscopic visualization. The United States of America represented by the Department of Health and Human Services, William Michael Hynes, Townsend and Townsend and Crew, March 15, 2005: US06867038 (5 worldwide citation)

A method of microdissection which involves forming an image field of cells of the tissue sample utilizing a microscope, identifying at least one zone of cells of interest from the image field of cells which at least one zone of cells of interest includes different types of cells than adjacent zones ...