1
Seizaburo Sakamoto, Masako Sakamoto: Method for inhibiting bone resorption and collagenase release. Vipont Laboratories, Eric P Schellin, April 5, 1988: US04735945 (15 worldwide citation)

Method of inhibiting bone resorption and collagenase release in mammalian periodontal subjects using a benzo-c-phenanthridine alkaloid compound.


2
Seizaburo Sakamoto, Katsumi Sugiyama: Method for inhibiting the release of histamine. Vipont Laboratories, Eric P Schellin, April 12, 1988: US04737503 (9 worldwide citation)

The present invention deals with the inhibition of histamine release from mammalian mast cells by contacting such cells with sanguinarine, a benzophenanthridine alkaloid.