1
Tarran Jones
Tsuchiya Masayuki, Sato Koh, Bendig Mary Margaret, Jones Steven Tarran, Saldanha Jose William: Reconstituted human antibody against human interleukin 6 receptor.. Chugai Pharmaceutical, December 14, 1994: EP0628639-A1 (54 worldwide citation)

A reconstituted human antibody against a human interleukin 6 receptor (IL-6R), which is composed of: (A) an L chain composed of (1) the C region of a human L chain and (2) the V region of an L chain comprising the framework region (FR) of a human L chain and the complementarity-determining region (C ...


2
Tarran Jones
Chesnut Robert W, Polley Margaret J, Paulson James C, Jones S Tarran, Saldanha Jose W, Bendig Mary M, Kriegler Michael, Perez Carl, Bayer Robert, Nunn Michael: Antibodies to p-selectin and their uses. Cytel, November 5, 1997: EP0804235-A1

The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized anti ...


3
Tarran Jones
Goldstein Neil I, Giorgio Nicholas A, Jones Steven Tarran, Saldanha Jose William: Antibody and antibody fragments for inhibiting the growth of tumors. Imclone Systems, April 1, 1998: EP0831880-A1

Chimerized and humanized versions of anti EGF receptor antibody 225 and fragments thereof for treatment of tumors.


4
Basi Guriq, Saldanha Jose W, Bard Frédérique: Humanized antibodies that recognize beta amyloid peptide. Neuralab, Wyeth, Basi Guriq, Saldanha Jose W, Bard Frédérique, MILASINCIC Debra J, December 16, 2004: WO/2004/108895 (60 worldwide citation)

The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aß in the brain of a patient. Preferred agents include antibodies, e.g., humanized antibodies.


5
Park John Edward, Garin Chesa Pilar, Bamberger Uwe, Leger Olivier, Saldanha Jose, Rettig Wolfgang J: Fapalpha-specific antibody with improved producibility. Boehringer Ingelheim Int, November 3, 1999: EP0953639-A1 (49 worldwide citation)

Recombinant antibody proteins are provided that specifically bind fibroblast activation protein alpha (FAP alpha ) and comprise framework modifications resulting in the improved producibility in host cells. The invention also relates to the use of said antibodies for diagnostic and therapeutic purpo ...


6
Basi Guriq, Saldanha Jose W, Yednock Ted: Humanized antibodies that recognize beta amyloid peptide. Neuralab, Wyeth, Basi Guriq, Saldanha Jose W, Yednock Ted, MANDRAGOURAS Amy E, September 23, 2004: WO/2004/080419 (36 worldwide citation)

The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A&bgr; in the brain of a patient. Preferred agents include humanized antibodies.


7
Hardman Norman, Kolbinger Frank, Saldanha Jose: Reshaped monoclonal antibodies against an immunoglobulin isotype.. Ciba-Geigy, Tanox Biosystems, March 30, 1994: EP0589840-A1 (12 worldwide citation)

The invention relates to reshaped human monoclonal antibodies directed against isotypic determinants of immunoglobulin E (IgE), direct equivalents and derivatives of said antibodies. The molecules of the invention are useful for diagnostics, prophylaxis and treatment of allergy.


8
Glaser Scott, Van, Vlijmen Herman, Lugovskoy Alexey Alexandrovich, Sanicola Nadel Michele, Wu Xiufeng, Garber Ellen, Saldanha Jose William: Cripto binding molecules. Biogen Idec Ma, Glaser Scott, Van, Vlijmen Herman, Lugovskoy Alexey Alexandrovich, Sanicola Nadel Michele, Wu Xiufeng, Garber Ellen, Saldanha Jose William, WILLIAMS Megan E, July 13, 2006: WO/2006/074397 (11 worldwide citation)

Humanized forms of an anti-CRIPTO antibody and portions thereof. In one embodiment, the variable regions of these antibodies or polypeptides comprising them (e.g., full-length antibodies or domain deleted antibodies) can be used to treat disorders, such as cancer.


9
SALDANHA Jose, NIJJAR Tarlochan S: [fr] ANTICORPS HUMANISÉS QUI RECONNAISSENT LALPHA-SYNUCLÉINE, [en] HUMANIZED ANTIBODIES THAT RECOGNIZE ALPHA-SYNUCLEIN. SALDANHA Jose, NIJJAR Tarlochan S, NEOTOPE BIOSCIENCES, LIEBESCHUETZ Joe, May 2, 2013: WO/2013/063516 (7 worldwide citation)

[en] The present application discloses humanized 9E4 antibodies. The antibodies bind to human alpha synuclein and can be used for immunotherapy of Lewy body disease.


10
Basi Guriq, Saldanha Jose W, Yednock Ted: Humanized antibodies that recognize beta amyloid peptide. Neuralab, Wyeth, January 11, 2006: EP1613347-A2 (6 worldwide citation)

The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Abeta in the brain of a patient. Preferred agents include humanized antibodies.