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Kevin Rodzinak
Furuyama Hidetomo, Goto Yasuhiro, Kawanishi Nobuhiko, Layton Mark E, Mita Takashi, Naya Akira, Ogino Yoshio, Onozaki Yu, Rodzinak Kevin J, Sakamoto Toshihiro, Sanderson Philip E, Wang Jiabing: Inhibitors of akt activity. Merck & Co, Banyu Pharmaceutical, Furuyama Hidetomo, Goto Yasuhiro, Kawanishi Nobuhiko, Layton Mark E, Mita Takashi, Naya Akira, Ogino Yoshio, Onozaki Yu, Rodzinak Kevin J, Sakamoto Toshihiro, Sanderson Philip E, Wang Jiabing, Leff Matthew A, December 10, 2009: WO/2009/148916 (10 worldwide citation)

The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms, preferably Akt1. The invention also provides for compositions comprising such inhibitory compounds and methods ...


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Moriya Minoru, Sakamoto Toshihiro, Kishino Hiroyuki, Kanatani Akio: (Ja) 2−アミノベンズイミダゾール誘導体, (En) 2-aminobenzimidazole derivative. Banyu Pharmaceutical, Moriya Minoru, Sakamoto Toshihiro, Kishino Hiroyuki, Kanatani Akio, BANYU PHARMACEUTICAL, April 15, 2004: WO/2004/031177 (45 worldwide citation)

(EN) A benzimidazole derivative represented by the general formula [I]: [I] wherein R1 and R2 each independently represents lower alkyl, etc.; R3 represents hydrogen, etc.; B1, B2, and B3 each represents hydrogen or lower alkyl; W represents a bond, -(CH2)-CONH-(CH2)-, etc.; Ar1 represents a 5- or 6 ...


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Nagata Hirotoshi C O Sumitomo, Minowa Junichiro C O Sumitomo, Yamada Manabu C O Sumitomo Cem, Ichikawa Junichiro C O Sumitom, Nayyer Jamshid C O Sumitomo Ce, Shimotsu Shinichi C O Sumitomo, Ogiwara Junichi C O Sumitomo C, Kobayashi Masanobu C O Sumitom, Honda Hideki C O Sumitomo Ceme, Kiuchi Kazumasa C O Sumitomo C, Shinriki Takashi C O Sumitomo, Sakamoto Toshihiro C O Sumitom: Optical waveguide device.. Sumitomo Cement Co, May 10, 1995: EP0652457-A1 (14 worldwide citation)

An optical waveguide device usable as an optical wave-modulator and having a reduced DC drift includes a LiNbO3 substrate (7), an optical waveguide formed in a front surface portion of the substrate, a dielectric layer (8) covering the front surface of the substrate and the optical waveguide surface ...


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Sakamoto Toshihiro, Sunami Satoshi, Yamamoto Fuyuki, Niiyama Kenji, Bamba Makoto, Takahashi Keiji, Furuyama Hidetomo, Sagara Takeshi, Otsuki Sachie, Nishibata Toshihide, Yoshizumi Takashi, Hirai Hiroshi: Dihydropyrazolopyrimidinone derivatives. Banyu Pharmaceutical, Sakamoto Toshihiro, Sunami Satoshi, Yamamoto Fuyuki, Niiyama Kenji, Bamba Makoto, Takahashi Keiji, Furuyama Hidetomo, Sagara Takeshi, Otsuki Sachie, Nishibata Toshihide, Yoshizumi Takashi, Hirai Hiroshi, Banyu Pharmaceutical, November 8, 2007: WO/2007/126122 (11 worldwide citation)

The invention relates to compounds of a general formula (I): wherein A1 is selected from the following formula (aa1); R1 is a lower alkenyl group or a lower alkynyl group; R2 is a phenyl, pyridyl or thienyl group; R5 and R6 are a hydrogen atom, a lower alkyl group or a hydroxy-lower alkyl group, etc ...


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Bamba Makoto, Furuyama Hidetomo, Niiyama Kenji, Sakamoto Toshihiro, Sunami Satoshi, Takahashi Keiji, Yamamoto Fuyuki, Yoshizumi Takashi: (Ja) ビシクロアニリン誘導体, (En) Bicycloaniline derivative. Banyu Pharmaceutical, Bamba Makoto, Furuyama Hidetomo, Niiyama Kenji, Sakamoto Toshihiro, Sunami Satoshi, Takahashi Keiji, Yamamoto Fuyuki, Yoshizumi Takashi, BANYU PHARMACEUTICAL, December 18, 2008: WO/2008/153207 (11 worldwide citation)

(EN) Disclosed are: a compound represented by the general formula (I); and others. (I) wherein A1 and A2 independently represent a nitrogen atom or a methine group which may be substituted; the ring B represents a 5- to 7-membered aliphatic ring or a spiro or bicyclo ring formed by the aliphatic rin ...


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Furuyama Hidetomo, Goto Yasuhiro, Kawanishi Nobuhiko, Layton Mark E, Mita Takashi, Ogino Yoshio, Onozaki Yu, Rossi Michael A, Sakamoto Toshihiro, Sanderson Philip E, Wang Jiabing: Inhibitors of akt activity. Merck & Co, Banyu Pharmaceutical, Furuyama Hidetomo, Goto Yasuhiro, Kawanishi Nobuhiko, Layton Mark E, Mita Takashi, Ogino Yoshio, Onozaki Yu, Rossi Michael A, Sakamoto Toshihiro, Sanderson Philip E, Wang Jiabing, Merck & Co, December 10, 2009: WO/2009/148887 (8 worldwide citation)

The instant invention provides for substituted [1,2,4]triazolo[4,3-a]-1,5-naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms, preferably Akt1. The invention also provides for compositions comprising such inhibi ...


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Naya Akira, Sakamoto Toshihiro, Haga Yuji, Otake Norikazu: (Ja) フェニルピリドン誘導体, (En) Phenylpyridone derivative. Banyu Pharmaceutical, Naya Akira, Sakamoto Toshihiro, Haga Yuji, Otake Norikazu, BANYU PHARMACEUTICAL, March 1, 2007: WO/2007/024004 (8 worldwide citation)

(EN) A compound represented by the formula (I) is contained as an active ingredient: wherein R1 and R2 independently represent a hydrogen atom, a lower alkyl group or the like, or R1 together with a nitrogen atom to which L, Z2 and R1 are attached may form an aliphatic nitrogenated heterocyclic grou ...


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Yorita Jun, Inazawa Shinji, Majima Masatoshi, Kashihara Hideki, Sakamoto Toshihiro, Toshioka Hideaki: Conductive paste and conductive film using it, plating method and production method for fine metal component. Sumitomo Electric Industries, June 9, 2004: EP1426978-A1 (7 worldwide citation)

The present invention provides with a conductive paste capable of further reducing the electrical resistance of a conductive film or the like, a conductive film having an anisotropic conductivity, a plating method for forming a plated coating having a uniform crystal structure throughout, and a prod ...



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