1
Eugene W Osikowicz, Michael Beggs, Paul Brookhart, Russell B Richerson, Frank Walsworth: Self-performing immunochromatographic device. Abbott Laboratories, Daniel R Curry, December 24, 1991: US05075078 (182 worldwide citation)

Improved chromatographic strip binding assay devices are provided for determining the presence or amount of an analyte present in a patient sample. Assay label reagents interact with capture reagents immobilized in a testing region on the strip substrate to generate a visually detectable image indic ...


2
Dinesh O Shah, Russell B Richerson: Chemiluminescent immunoassay for antibody detection. Abbott Laboratories, Cheryl L Becker, Priscilla E Porenbski, January 6, 1998: US05705330 (34 worldwide citation)

A chemiluminescent assay utilizing a precomplex reagent of a probe comprising an enhancer compound such as a hapten and a conjugate comprising a chemiluminescent signal generating compound. Kits for performing such an chemiluminescent assay are also provided.


3
Thierry Dervieux, Russell B Richerson: Methods for direct detection of individual methotrexate metabolites. Prometheus Laboratories, Townsend and Townsend and Crew, July 26, 2005: US06921667 (4 worldwide citation)

The present invention provides a method for determining a level of a methotrexate polyglutamate (MTXPG) in a cellular extract by resolving at least one MTXPG in a cellular extract obtained from a human undergoing methotrexate therapy; and detecting at least one resolved MTXPG, thereby determining a ...


4
Thierry Dervieux, Russell B Richerson: Methods of quantifying methotrexate metabolites. Cypress Bioscience, Cooley Godward & Kronish LI, July 21, 2009: US07563590

The present invention provides a method for efficiently converting methotrexate polyglutamates to methotrexate in a cellular extract by contacting the cellular extract with gamma glutamyl hydrolase under conditions suitable for efficient conversion of methotrexate polyglutamates to methotrexate.


5
Thierry Dervieux, Russell B Richerson: Methods for direct detection of individual methotrexate metabolites. Cathryn Campbell, McDERMOTT WILL & EMERY, September 9, 2004: US20040175834-A1

The present invention provides a method for determining a level of a methotrexate polyglutamate (MTXPG) in a cellular extract by resolving at least one MTXPG in a cellular extract obtained from a human undergoing methotrexate therapy; and detecting at least one resolved MTXPG, thereby determining a ...


6
Thierry Dervieux, Russell B Richerson: Methods of quantifying methotrexate metabolites. Campbell & Flores, March 4, 2004: US20040043441-A1

The present invention provides a method for efficiently converting methotrexate polyglutamates to methotrexate in a cellular extract by contacting the cellular extract with gamma glutamyl hydrolase under conditions suitable for efficient conversion of methotrexate polyglutamates to methotrexate.


7
Thierry Dervieux, Russell B Richerson: Methods of Quantifying Methotrexate Metabolites. Exagen Diagnostics, October 27, 2011: US20110262948-A1

The present invention provides a method for efficiently converting methotrexate polyglutamates to methotrexate in a cellular extract by contacting the cellular extract with gamma glutamyl hydrolase under conditions suitable for efficient conversion of methotrexate polyglutamates to methotrexate.