1
Francis V Lamberti, Richard Chris Klann, Ronald Stewart Hill: Cross-linked bioactive hydrogel matrices. Pioneer Surgical Orthobiologics, Womble Carlyle Sandridge & Rice PLLC, September 21, 2010: US07799767 (58 worldwide citation)

The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight componen ...


2
Francis V Lamberti, Richard Chris Klann, Ronald Stewart Hill: Immobilized bioactive hydrogel matrices as surface coatings. Encelle, Alston & Bird, December 4, 2007: US07303814 (43 worldwide citation)

The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydro ...


3
Francis V Lamberti, Richard Chris Klann, Ronald Stewart Hill: Method of preparing cross-linked bioactive hydrogel matrices. Encelle, Womble Carlyle Sandridge & Rice, November 8, 2011: US08053423 (14 worldwide citation)

The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight componen ...


4
Francis V Lamberti, Richard Chris Klann, Ronald Stewart Hill: Immobilized bioactive hydrogel matrices as surface coatings. Pioneer Surgical Technology, Womble Carlyle Sandridge & Rice, December 17, 2013: US08609122 (2 worldwide citation)

The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydro ...


5
Francis Vincent Lamberti, Richard Chris Klann, Ronald Stewart Hill: Bone implant materials comprising cross-linked bioactive hydrogel matrices. Pioneer Surgical Technology, Womble Carlyle Sandridge & Rice, February 17, 2015: US08957050 (1 worldwide citation)

The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight componen ...


6
Francis V Lamberti, Richard Chris Klann, Ronald Stewart Hill: Cross-linked bioactive hydrogel matrices. Pioneer Surgical Technology, Womble Carlyle Sandridge & Rice, March 4, 2014: US08664202 (1 worldwide citation)

The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight componen ...


7
Francis Vincent Lamberti, Richard Chris Klann, Ronald Stewart Hill: Bone implant materials comprising cross-linked bioactive hydrogel matrices. RTI Surgical Technology, Womble Carlyle Sandridge & Rice, April 18, 2017: US09623146

The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight componen ...


8
Francis Vincent Lamberti, Richard Chris Klann, Ronald Stewart Hill: Immobilized bioactive hydrogel matrices as surface coatings. RTI Surgical, Womble Carlyle Sandridge & Rice, April 4, 2017: US09610382

The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydro ...


9
Francis Vincent Lamberti, Ronald Stewart Hill, Adam MacMillan, Edward Ahn, Brian Schlossberg, Stephen Capistron, William H Lloyd: Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith. Pioneer Surgical Technology, Womble Carlyle Sandridge & Rice, January 27, 2015: US08940317

The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the c ...


10
Francis Vincent Lamberti, Ronald Stewart Hill, Adam MacMillan, Edward Ahn, Brian Schlossberg, Stephen Capistron, William H Lloyd: Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith. RTI Surgical, Womble Carlyle Sandridge & Rice, June 21, 2016: US09370608

The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the c ...