1
Della Valle Francesco, Romeo Aurelio, Lorenzi Silvana: Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same.. Fidia, April 24, 1985: EP0138572-A2 (127 worldwide citation)

Two pharmaceutically useful fractions of hyaluronic acid are obtained comprising a first fraction with a molecular weight between 50,000 and 100,000 which is useful for wound healing, and a second fraction having a molecular weight between 500,000 and 730,000 which is useful for intraocular and intr ...


2
Della Valle Francesco Dr, Romeo Aurelio Prof: Crosslinked carboxy polysaccharides.. Fidia, November 15, 1989: EP0341745-A1 (120 worldwide citation)

Inter and/or intramolecular cross-linked esters of acid polysaccharides are disclosed in which a part or all of the carboxy groups are esterified with hydroxyl groups of the same molecule and/or of different molecules of the acid polysaccharide. These inner cross-linked esters of polysaccharide acid ...


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Della Valle Francesco, Romeo Aurelio, Lorenzi Silvana: New medicaments for topical use.. Fidia, October 15, 1986: EP0197718-A2 (93 worldwide citation)

Pharmaceutical preparations for non-topical administration containing a pharmacologically active substance together with hyaluronic acid or a molecular weight fraction thereof. The hyaluronic acid may be in the form of the free acid or may be a salt with an alkali or alkaline earth metal, magnesium, ...


5
Della Valle Francesco, Romeo Aurelio: Cross-linked esters of hyaluronic acid.. Fidia, April 27, 1988: EP0265116-A2 (55 worldwide citation)

Cross-linked esters of hyaluronic acid are provided which result from the esterification of polyhydric alcohols with two or more carboxy groups of the hyaluronic acid polysaccharide. These cross-linked esters are useful in the field of biodegradable plastics for sanitary and surgical articles and in ...


6
Della Valle Francesco, Romeo Aurelio, Lorenzi Silvana: Fractions dacide hyaluronique ayant une activite pharmaceutique et procede de preparation, Hyaluronic acid fractions having pharmaceutical activity, and processes for the preparation thereof. Fidia, BORDEN LADNER GERVAIS, May 27, 1986: CA1205031 (38 worldwide citation)

Abstract of the DisclosureTwo pharmaceutically useful fractions of hyaluronic acidare obtained comprising a first fraction with a molecularweight between 50,000 and 100,000 which is useful for woundhealing, and a second fraction having a molecular weightbetween 500,000 and 730,000 which is useful fo ...


7
Valle Francesco Della, Romeo Aurelio: Polysaccharide esters and their salts. Fidia, February 14, 1996: EP0696598-A1 (30 worldwide citation)

The invention concerns the esters of hyaluronic acid in which all or only a portion of the carboxylic groups of the acid are esterified, and the salts of the partial esters with metals or with pharmacologically acceptable organic bases. The compounds possess interesting and precious bioplastic and p ...


8
Callegaro Lanfranco, Romeo Aurelio, Benedetti Luca: Process for the preparation of microspheres containing biologically active components.. Fidia, December 9, 1992: EP0517565-A2 (26 worldwide citation)

The present invention is directed to a microsphere for the controlled release of a biologically active molecule which comprises a biologically active molecule and an ester of hyaluronic acid or mixtures of said esters of hyaluronic acids, and wherein said biologically active molecule is surrounded b ...


9
Della Valle Francesco, Romeo Aurelio: Esters of alginic acid.. Fidia, January 7, 1988: EP0251905-A2 (22 worldwide citation)

The present invention relates to total and partial esters of alginic acid with alcohols of the aliphatic, araliphatic, cycloaliphatic, aliphatic-cycloaliphatic and heterocyclic radicals, and salts of said partial esters with inorganic and organic bases. The said partial ester are not a partial ester ...


10
Della Valle Francesco Dr, Romeo Aurelio Prof: New polysaccharide esters.. Fidia, November 23, 1989: EP0342557-A1 (20 worldwide citation)

New polysaccharide esters are disclosed, and more precisely esters of acidic polysaccharides chosen from the group formed by carboxymethylcellulose, carboxymethyl starch and carboxymethylchitin. These new esters and some esters of the type already known are useful as medicaments, for the manufacture ...



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