1
Roger W Giese, Samy Abdel Baky, Linxiao Xu: Release tag compounds producing ketone signal groups. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, May 14, 1996: US05516931 (63 worldwide citation)

A release tag reagent suitable for use in the chemical analysis of a substance to be detected comprises signal, release, and reactivity groups. A class of release tag compounds that are cleaved to release as signal groups very stable electrophoric ketones which are sufficiently volatile for determin ...


2
Roger W Giese: Biochemical avidin-biotin multiple-layer system. Richard P Crowley, August 4, 1981: US04282287 (61 worldwide citation)

A multiple-layer process for applying, in alternate, successive layers, the protein, avidin, and a biotin-containing extender material to a solid surface to modify the properties of the surface and to the multiple-layer product so prepared.


3
Roger W Giese: Method of chemical analysis employing molecular release tag compounds. Weingarten Schurgin Gagnebin & Hayes, March 17, 1987: US04650750 (61 worldwide citation)

A method of chemical analysis is disclosed which employs a release tag compound of general formula


4
Roger W Giese: Molecular analytical release tags and their use in chemical analysis. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, November 1, 1994: US05360819 (59 worldwide citation)

A release tag reagent suitable for use in the chemical analysis of a substance to be detected, which substance contains reactive groups, such as for, but not limited to gas phase detection groups, which reagent comprises three covalently bonded groups: a signal group which on release provides a keto ...


5
Roger W Giese: Molecular analytical release tags and their use in chemical analysis. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, November 24, 1987: US04709016 (52 worldwide citation)

A new class of chemical reagents called release tags which comprise signal, release and reactivity groups is disclosed and a release tag involving a pentafluorobenzoyl signal group, a methionylamide release group, and an active ester reactivity group is used to analyze the hormone, thyroxine, in ser ...


6
Roger W Giese, Samy Abdel Baky, Kariman Allam: Molecular analytical release tags and their use in chemical analysis. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, July 22, 1997: US05650270 (42 worldwide citation)

Analytical reagents designated "release tags", for labeling molecular species with a highly detectable signal group which can be released in the form of a volatile compound at a desired point in an analytical procedure. In one embodiment, the release tags have the formula


7
Roger W Giese, Samy Abdel Baky, Linxiao Xu: Release tag compounds producing ketone signal groups. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, February 11, 1997: US05602273 (41 worldwide citation)

A release tag reagent suitable for use in the chemical analysis of a substance to be detected comprises signal, release, and reactivity groups. A class of release tag compounds that are cleaved to release as signal groups very stable electrophoric ketones which are sufficiently volatile for determin ...


8
Roger W Giese: Process for applying multiple layers of a protein and a ligand extender to a surface and to the multiple-layer system. Richard P Crowley, October 23, 1984: US04478914 (40 worldwide citation)

A multiple-layer process for applying, in alternate, successive molecular layers, a protein material, and a ligand extender material to a surface to modify the properties of the surface and to the multiple-layer product so prepared.


9
Roger W Giese, Samy Abdel Baky, Linxiao Xu: Release tag compounds producing ketone signal groups. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, February 18, 1997: US05604104 (34 worldwide citation)

A release tag reagent suitable for use in the chemical analysis of a substance to be detected comprises signal, release, and reactivity groups. A class of release tag compounds that are cleaved to release as signal groups very stable electrophoric ketones which are sufficiently volatile for determin ...


10
Roger W Giese, Samy Abdel Baky, Linxiao Xu: Release tag compounds producing ketone signal groups. Northeastern University, Weingarten Schurgin Gagnebin & Hayes, March 11, 1997: US05610020 (33 worldwide citation)

A release tag reagent suitable for use in the chemical analysis of a substance to be detected comprises signal, release, and reactivity groups. A class of release tag compounds that are cleaved to release as signal groups very stable electrophoric ketones which are sufficiently volatile for determin ...



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