31
Rodney W Salo, Julio C Spinelli, Bruce H KenKnight: Apparatus and method for spatially and temporally distributing cardiac electrical stimulation. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, October 28, 2003: US06640135 (36 worldwide citation)

A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocar ...


32
Joseph Walker, Rodney W Salo, Anand Iyer, Joseph M Pastore, Eric Mokelke: Systems and methods for electrical stimulation of blood vessels. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, May 14, 2013: US08442639 (32 worldwide citation)

Disclosed herein, among other things, is a system for electrical stimulation of blood vessels. An embodiment of the system includes at least one electrode having electrical contact with a blood vessel. The embodiment also includes a stimulation circuit electrically connected to the electrode, the ci ...


33
Rodney W Salo, Joseph M Pastore, Jeffrey E Stahmann, Jesse W Hartley: Therapy control based on the rate of change of intracardiac impedance. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, May 20, 2008: US07376463 (30 worldwide citation)

A system comprising a medical device that includes an impedance measurement circuit adapted to be coupled to implantable electrodes to obtain an intracardiac impedance signal between electrodes, a therapy circuit operable to deliver a therapy to a subject, and a controller circuit coupled to the imp ...


34
Evgenia Mandrusov, Paul Consigny, Rodney W Salo: Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, December 2, 2008: US07460914 (27 worldwide citation)

A method for stimulating angiogenesis is provided that includes the use of an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be electrically connected to the electrical output channel and a distal end adapted to be placed in the b ...


35
Joseph M Pastore, Julio C Spinelli, Helen L Reeve, Jeffrey Ross, Rodney W Salo, Allan Shuros: Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, January 22, 2008: US07320675 (26 worldwide citation)

A drug delivery system detects a cardiac condition indicative of a need for increasing a cardiac metabolic level and, in response, releases a drug into tissue or blood to shift a source of metabolically synthesized energy fueling cardiac contraction from fatty acid to glucose. One example of such a ...


36
Evgenia Mandrusov, Paul Consigny, Rodney W Salo: Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, July 15, 2008: US07400931 (24 worldwide citation)

A device that includes an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be electrically connected to the electrical output channel and a distal end adapted to be placed in the blood conduit where the distal end of the lead is ada ...


37
Marina Brockway, Joseph M Pastore, Yi Zhang, Carlos Ricci, Allan Shuros, Rodney W Salo: Method and apparatus for delivering chronic and post-ischemia cardiac therapies. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, February 23, 2010: US07668594 (22 worldwide citation)

An implantable cardiac rhythm management (CRM) device delivers a chronic therapy while detecting an ischemic state. When the ischemic state indicates the occurrence of an ischemic event, the implantable CRM device delivers a post-ischemia therapy. The post-ischemia therapy and the chronic therapy ar ...


38
Rodney W Salo, Julio C Spinelli, Bruce H KenKnight: Apparatus and method for spatially and temporally distributing cardiac electrical stimulation. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, November 6, 2007: US07292887 (17 worldwide citation)

A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocar ...


39
Jesse W Hartley, Joseph M Pastore, Rodney W Salo, Andrew P Kramer, Jeffrey E Stahmann: Method and apparatus for controlling cardiac therapy using ultrasound transducer. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, March 29, 2011: US07914452 (17 worldwide citation)

A cardiac rhythm management (CRM) system provides for post-myocardial infarction (MI) therapy with closed-loop control using one or more ultrasound transducers sensing one or more ultrasound signals indicative of cardiac dimensions. Cardiac size parameters are produced using the one or more ultrasou ...


40
Andrew P Kramer, Rodney W Salo, Julio C Spinelli, Bruce H KenKnight: Method for reversal of myocardial remodeling with electrical stimulation. Cardiac Pacemakers, Schwegman Lundberg & Woessner P A, June 16, 2009: US07548782 (16 worldwide citation)

A method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened p ...