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David J Grainger, James C Metcalfe, Lawrence L Kunz, Robert W Schroff, Peter L Weissberg: Prevention and treatment of cardiovascular pathologies. NeoRx Corporation, Schwegman Lundberg Woessner & Kluth P A, June 23, 1998: US05770609 (99 worldwide citation)

A method for treating or preventing cardiovascular pathologies by administering a compound of the formula (I): ##STR1## wherein Z is C.dbd.O or a covalent bond; Y is H or O(C.sub.1 -C.sub.4)alkyl, R.sup.1 and R.sup.2 are individually (C.sub.1 -C.sub.4)alkyl or together with N are a saturated heteroc ...


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Paul G Abrams, Robert W Schroff, Alton C Morgan Jr: Methods for improved targeting of antibody, antibody fragments, hormones and other targeting agents, and conjugates thereof. NeoRx Corporation, Seed and Berry, July 23, 1991: US05034223 (26 worldwide citation)

Methods for improved targeting of antibody, antibody fragments, peptides hormones, steroid hormones and conjugates thereof are disclosed. Enhanced delivery to target cells of antibodies or fragments thereof or other receptor-mediated delivery system, such as peptide, specific for a population of cel ...


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Paul G Abrams, Robert W Schroff, Alton C Morgan Jr: Methods for improved targeting of antibody, antibody fragments, hormones and other targeting agents, and conjugates thereof. NeoRx Corporation, Schwegman Lundberg Woessner & Kluth P A, February 25, 2003: USRE038008

Methods for improved targeting of antibody, antibody fragments, peptides hormones, steroid hormones and conjugates thereof are disclosed. Enhanced delivery to target cells of antibodies or fragments thereof or other receptor-mediated delivery system, such as peptide, specific for a population of cel ...


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David J Grainger, James C Metcalfe, Lawrence L Kunz, Robert W Schroff: Prevention and treatment of cardiovascular pathologies with tamoxifen analogues. NeoRx Corporation, Schwegman Lundberg Woessner & Kluth Pa, June 6, 2002: US20020068731-A1

A method for treating or preventing cardiovascular pathologies by administering a compound of the formula (I): 1 wherein Z is CO or a covalent bond; Y is H or O(C1-C4)alkyl, R1 and R2 are individually (C1-C4)allyl or together with N are a saturated heterocyclic group, R3 is ethyl or chloroethyl, R4 ...


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Robert W Schroff: Use of chymase inhibitors for the prevention and/or treatment of arterio-venous graft failure. Brian R Morrill, Biomeasure Incorporated, July 6, 2006: US20060148833-A1

Disclosed is a method of treating A-V graft failure in a subject in need of such treatment, said method comprising administering to said subject an effective amount of an agent that inhibits the production, release or neo-intima generating effects of chymase, wherein said effective amount of said ag ...


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David J Grainger, James C Metcalfe, Lawrence L Kunz, Robert W Schroff: Prevention and treatment of cardiovascular pathologies with tamoxifen analogues. NeoRx Corporation, Schwegman Lundberg Woessner & Kluth Pa, June 22, 2006: US20060135560-A1

A method for treating or preventing cardiovascular pathologies by administering a compound of the formula (I): wherein Z is C═O or a covalent bond; Y is H or O(C1-C4)alkyl, R1 and R2 are individually (C1-C4)alkyl or together with N are a saturated heterocyclic group, R3 is ethyl or chloroethyl, R4 i ...


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