1
Blake Alan Rowe, Robert Steven Siegel, Steven Lee Wagner: Peptide and peptide analog protease inhibitors. SIBIA Neurosciences, Stephanie L Brown Martin Haller & McClain Seidman, February 3, 1998: US05714471 (10 worldwide citation)

Methods of use of compounds and compounds for the treatment of disorders characterized by the cerebral deposition of amyloid are provided. Among the compounds are those of formulae I and II: ##STR1## in which R.sub.1 is preferably 2-methyl propene, 2-butene, cyclohexyl or cyclohexylmethyl; R.sub.2, ...


2
Ian Alexander McDonald, Elisabeth Albrecht, Benito Munoz, Blake Alan Rowe, Robert Steven Siegel, Steven Lee Wagner: Peptide and peptide analog protease inhibitors. SIBIA Neurosciences, Stephanine L Heller Ehrman White & McAuliffe Seidman, October 5, 1999: US05962419 (9 worldwide citation)

Methods of use of compounds for the treatment of disorders characterized by the cerebral deposition of amyloid are provided. Among the compounds provided for use in the methods are those of the formula: ##STR1## in which R.sub.1 is preferably 2-methylpropenyl, 2-butenyl, cyclohexyl or cyclohexylmeth ...


3
Blake Alan Rowe, Robert Steven Siegel, Steven Lee Wagner: Methods for identifying compounds effective for treating neurodegenerative disorders and for monitoring the therapeutic intervention therefor. SIBIA Neurosciences, Stephanie L Heller Ehrman White & McAuliffe Seidman, November 28, 2000: US06153171 (4 worldwide citation)

Methods for identifying compounds that can be used for treatment of neurodegenerative diseases, for monitoring the progression of these diseases, and for monitoring therapeutic intervention of these diseases are provided. These methods are effected by determining the relative amount of .alpha.-sAPP ...