1
Robert S Kieval, Peter T Keith, Matthew M Burns, Thomas R Hektner, Gina L Hansen: Devices and methods for cardiovascular reflex control. CVRx, Townsend and Townsend and Crew, February 18, 2003: US06522926 (645 worldwide citation)

Devices, systems and methods by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. By selectively and controllably activating baroreceptors, the present invention reduces excessive blood pressure, sym ...


2
Robert S Kieval, Tom D Bettett, Stephanie Michele Fitts: Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure. Medtronic, Harold R Patton, Reed A Duthler, June 6, 2000: US06073048 (473 worldwide citation)

A system and method for stimulating the baroreflex arc based on levels of indicators from the body includes a pacemaker for bradycardia support pacing should the indicators show the need for support pacing. Other indicators and a process take advantage of an assumed relationship between peripheral v ...


3
Robert S Kieval: Drug delivery neural stimulation device for treatment of cardiovascular disorders. Medtronic, Michael B Atlass, Harold R Patton, January 23, 2001: US06178349 (410 worldwide citation)

An implantable medical device for treatment of cardiovascular disorders by stimulating a selective nerve, the device including an implantable pulse generator, an implantable electrode body and a reservoir. The electrode body includes an electrode electrically connected to the pulse generator. Furthe ...


4
Robert S Kieval, Bruce J Perrson, David J Serdar, Peter T Keith: Stimulus regimens for cardiovascular reflex control. CVRx, Townsend and Townsend and Crew, January 10, 2006: US06985774 (343 worldwide citation)

Devices, systems and methods by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, for example a baroreceptor in the carotid sinus. ...


5
Robert S Kieval: System for providing hyperpolarization of cardiac to enhance cardiac function. Medtronic, Harold R Patton, Michael B Atlass, September 1, 1998: US05800464 (342 worldwide citation)

An implantable system providing cardiac anodal stimulation (AS) as a system for effecting hyperpolarization of myocardial cells of a heart chamber to enhance the relaxation thereof in the diastolic phase and to thereby enhance cardiac function. The AS system is optimally timed to be delivered in an ...


6
Robert S Kieval, Bruce J Persson, David J Serdar, Peter T Keith: Mapping methods for cardiovascular reflex control devices. CVRx, Townsend & Townsend and Crew, February 1, 2005: US06850801 (321 worldwide citation)

Devices, systems and methods by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably in the carotid sinus. A mapping method ...


7
Robert S Kieval: Systems and method for controlling renovascular perfusion. CVRX, Townsend and Townsend and Crew, September 9, 2003: US06616624 (289 worldwide citation)

Devices, systems and methods by which the real or apparent renovascular perfusion and intrarenal pressure may be selectively and controllably increased. By selectively and controllably increasing renovascular perfusion and interstitial hydrostatic pressure when the heart is unable to pump sufficient ...


8
Robert S Kieval: Cardiac arrhythmia management by application of adnodal stimulation for hyperpolarization of myocardial cells. Medtronic, Harold R Patton, Michael B Atlass, September 29, 1998: US05814079 (288 worldwide citation)

An anodal stimulation method and apparatus for the prevention or treatment of tachyarrhythmias using anodal stimulation (AS) energy for effecting hyperpolarization of myocardial cells of a heart chamber to enhance the relaxation thereof in the diastolic phase and to enhance cardiac function, reverse ...


9
Robert S Kieval, Orhan Soykan: Method and apparatus to optimize pacing based on intensity of acoustic signal. Medtronic, Harold R Patton, Michael B Atlass, September 10, 1996: US05554177 (272 worldwide citation)

An acoustic sensor is located in association with a patient's heart to detect abnormal heart sounds and a processor isolates abnormal heart sounds therefrom. The characteristics of these heart sounds are monitored while adjustments are made to the timing of pacing pulses to achieve a better heart fu ...


10
Robert S Kieval, Tommy D Bennett: Method and apparatus for optimizing pacemaker AV delay. Medtronic, Michael B Atlass, Harold R Patton, May 6, 1997: US05626623 (258 worldwide citation)

In a dual chamber cardiac pacemaker, a method and apparatus for determining an atrioventricular (AV) delay interval to maintain optimal left heart AV mechanical synchrony and function. When the intrinsic or paced atrial heart rate is stable, test AV delay intervals are selected and delivered as righ ...