1
Robert R Alfano, Scott Alfano, Quan Zhen Wang, Ping Pei Ho: Remote-controllable, micro-scale device for use in in vivo medical diagnosis and/or treatment. Kriegsman & Kriegsman, May 29, 2001: US06240312 (492 worldwide citation)

Remote-controllable, micro-scale, robotic device for use in diagnosing and/or treating abnormalities inside a human body in vivo. The device has a length from 0.1 mm to 10 mm and can be introduced into the body either from natural body openings or by injection into the blood stream. Once inside the ...


2
Robert R Alfano: Method and apparatus for detecting the presence of caries in teeth using visible light. Irving M Kriegsman, October 30, 1984: US04479499 (233 worldwide citation)

A method and apparatus for detecting the presence of caries in human teeth using visible light. The tooth is exposed to light of relatively narrow bandwidths. The light from the tooth is preferably examined by two photomultipliers or visually each examining a different wavelength. Caries are detecte ...


3
Robert R Alfano, Cheng H Liu, Wenling S Glassman: Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy. Kriegsman & Kriegsman, November 16, 1993: US05261410 (224 worldwide citation)

A method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue. The present method is based on the discovery that, when irradiated with a beam of infrared, monochromatic light, malignant tumor tissue, benign tumor tissue, and normal or benign ti ...


4
Robert R Alfano, Cheng H Liu: Method for distinguishing between calcified atherosclerotic tissue and fibrous atherosclerotic tissue or normal cardiovascular tissue using Raman spectroscopy. Kriegsman & Kriegsman, March 15, 1994: US05293872 (208 worldwide citation)

A method for distinguishing between calcified atherosclerotic tissue and either fibrous atherosclerotic tissue or normal cardiovascular tissue. The present method is based on the discovery that, when irradiated with a beam of monochromatic infrared light, calcified atherosclerotic human aortic tissu ...


5
Robert R Alfano, Stavros G Demos: Imaging and characterization of tissue based upon the preservation of polarized light transmitted therethrough. The Research Foundation of City College of New York, Kriegsman & Kriegsman, February 17, 1998: US05719399 (205 worldwide citation)

A method and apparatus for imaging and/or characterizing a tissue based upon the extent to which initially polarized light maintains its polarization after propagating through the tissue. In a preferred embodiment, the present invention relates to a method for identifying a tissue in question, the m ...


6
Robert R Alfano, Michele A Alfano: Method for detecting cancerous tissue using visible native luminescence. Irving M Kriegsman, June 5, 1990: US04930516 (195 worldwide citation)

A method and apparatus for detecting the presence of cancerous tissue using visible luminescence. The tissue to be examined is excited with a beam of monochromatic light that causes the tissue to fluoresce over a spectrum of wavelengths. The intensity at which the excited tissue fluoresces can be me ...


7
Robert R Alfano, Wubao Wang: Method and system for examining biological materials using low power CW excitation raman spectroscopy. The Research Foundation of CUNY, Kriegsman & Kriegsman, November 21, 2000: US06151522 (183 worldwide citation)

A method and system for examining biological materials using low-power cw excitation Raman spectroscopy. In accordance with the teachings of the invention, a low-power continuous wave (cw) pump laser beam and a low-power cw Stokes (or anti-Stokes) probe laser beam simultaneously illuminate a biologi ...


8
Robert R Alfano, Yury Budansky: Method and apparatus for in vivo examination of subcutaneous tissues inside an organ of a body using optical spectroscopy. The Research Foundation of City College of New York, Kriegsman & Kriegsman, November 9, 1999: US05983125 (158 worldwide citation)

Method and apparatus for examining subcutaneous tissues inside organs of the body. The method comprises the steps of (a) providing an optic probe positioning assembly comprising a solid needle and a hollow tube, the solid needle being sheathed inside the hollow tube; (b) subcutaneously inserting the ...


9
Robert R Alfano: Method and apparatus for detecting cancerous tissue using luminescence excitation spectra. Irving M Kriegsman, August 27, 1991: US05042494 (135 worldwide citation)

A method and apparatus for detecting the presence of cancerous tissue using native visible luminescence. The tissue to be examined is excited with a beam of monochromatic light that causes the tissue to fluoresce over a spectrum of wavelengths. The intensity at which the excited tissue fluoresces ca ...


10
Robert R Alfano, Bidyut Das, Guichen Tang: Method and apparatus for distinguishing cancerous tissue from benign tumor tissue, benign tissue or normal tissue using native fluorescence. Mediscience Technology, Kriegsman & Kriegsman, July 21, 1992: US05131398 (127 worldwide citation)

A method and apparatus for distingishing cancerous tumors and tissue from benign tumors and tissue or normal tissue using native fluorescence. The tissue to be examined is excited with a beam of monochromatic light at 300 nanometers (nm). The intensity of the native fluorescence emitted from tissue ...