1
Robert J Levis, Louis J Romano: Vaporization and sequencing of nucleic acids. Wayne State University, Reising Ethington Barnard & Perry, December 3, 1996: US05580733 (126 worldwide citation)

Method for analyzing a nucleic acid molecule, without fragmenting the molecule, by vaporizing a mixture of the molecule and a matrix by illuminating the mixture with visible laser light absorbed by the matrix and not by the nucleic acid molecule. The method is useful for determining the nucleotide s ...


2
Robert J Levis, Louis J Romano: Method for analyzing an organic sample. Wayne State University, Brooks & Kushman, May 11, 1993: US05210412 (87 worldwide citation)

Described is a method and apparatus for analyzing an organic sample. In the preferred embodiment, this method and apparatus allows the determination of the base sequence of a nucleic acid by determining the molecular weights of the components of a biological sample. The method uses either a pre-exis ...


3
Nicholas V Coppa, Robert J Levis: Control of particle formation at the nanoscale. April 1, 2014: US08685293 (9 worldwide citation)

Our invention allows for control of particle formation at the nanoscale, providing a means to control nanoparticle and nanostructure formation using feedback on the fly from nanoparticle characteristic analysis and optimization/knowledge extraction control algorithms. A closed loop feedback controll ...


4
Robert J Levis, John J Brady, Elizabeth J Judge: Vaporization device and method for imaging mass spectrometry. Temple University of the Commonwealth System of Higher Education, RatnerPrestia, December 3, 2013: US08598521

Methods and apparatus for analyzing samples are disclosed. The samples are analyzed by vaporizing molecules from a sample in a sample area with a femtosecond laser beam under ambient conditions, ionizing the vaporized molecules with electrospray ionization under the ambient conditions to form ions; ...


5
Robert J Levis, Johanan H Odhner: Filament-based stimulated Raman detection. Temple University —Of The Commonwealth System of Higher Education, Drinker Biddle & Reath, April 7, 2015: US09001325

In apparatus and methods of Raman spectroscopy in air, a target region is excited by a laser pump pulse exceeding the critical power for self-focusing in air and having a duration after self-focusing of 15 fs or less. A laser probe pulse having a duration in the range of 200 fs to 100 ps and an ener ...


6
Herschel Rabitz, Elmar Schreiber, Robert J Levis: Quantum dynamic discriminator for molecular agents. Woodcock Washburn, July 1, 2004: US20040128081-A1

The disclosed invention is related to the field of quantum dynamic discriminators, sample identification systems, mass spectrometers and methods for identifying a component in a composition. Also disclosed are quantum dynamic discriminators and methods for ascertaining the quantum dynamic states of ...


7
Robert J Levis, John J Brady, Elizabeth J Judge: Vaporization device and method for imaging mass spectrometry. June 14, 2012: US20120149009-A1

Methods and apparatus for analyzing samples are disclosed. The samples are analyzed by vaporizing molecules from a sample in a sample area with a femtosecond laser beam under ambient conditions, ionizing the vaporized molecules with electrospray ionization under the ambient conditions to form ions; ...