11
Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Martin Karl Russel Burnham, Robert H Reid Jr, Robert King Stodola, Phillip N Zarfos: Era of Streptococcus pneumoniae. SmithKline Beecham Corporation, Edward R Gimmi, Thomas S Deibert, William T King, December 26, 2000: US06165989 (1 worldwide citation)

The invention provides era polypeptides and DNA (RNA) encoding era polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing era polypeptides to screen for antibacterial compounds.


12
Paul R Burnett, John E van Hamont, Robert H Reid, Jean A Setterstrom, Thomas C Van Cott, Deborah L Birx: Vaccines against intracellular pathogens using antigens encapsulated within biodegradable-biocompatible microspheres. The United States of America represented by the Secretary of the Army, Elizabeth Arwine, June 23, 2009: USRE040786

This invention relates to parenteral and mucosal vaccines against diseases caused by intercellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).


13
Daniel L Jarboe, Robert H Reid, Edgar C Boedeker, Frederick J Cassels: Oral-intestinal vaccines against diseases caused by enteropathic organisms using antigens encapsulated within biodegradable-biocompatible microspheres. The United States of America represented by the Secretary of the Army, Elizabeth Arwine, October 20, 2009: US07604811

This invention is directed to oral-intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.


14
Robert H Reid, John E VanHamont, William R Brown, Edgar C Boedeker, Curt Thies: Microparticle carriers of maximal uptake capacity by both M cells and non-M cells. The United States of America represented by the Secretary of the Army, Elizabeth Arwine, March 2, 2010: USRE041157

In a solvent extraction process for preparing microspheres of a biodegradable polymer, the improvement comprising: preparing a homogenized antigen-sucrose matrix and adding a solvent to the sucrose-antigen matrix to form a solution; preparing a solution of a biodegradable polymer by adding a solvent ...


15
Robert H Reid, Jean A Setterstrom, Edgar Boedeker, John VanHamont, Charles McQueen, Frederick Cassels: Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres. Nash & Titus, August 28, 2003: US20030161889-A1

This invention relates to an immunostimulating composition comprising encapsulating microspheres, which may contain a pharmaceutically-acceptable adjuvant, wherein said microspheres having a diameter between 1 nanometer (nm) to 10 microns (um) are comprised of (a) a biodegradable-biocompatible poly( ...


16
Jeffrey L Nauss, Robert H Reid, Marcia Wolf, Scheherazade Sadegh Nasseri: Model for testing immunogencity of peptides. Nash & Titus, May 1, 2003: US20030082193-A1

Assay methods for determining whether a peptide is likely to be immunogenic are based on a computer modeling of binding to a Class II MHC DR1 receptor. This is confirmed by competitive inhibition binding assays. The peptides are useful for eliciting an immune response for vaccination or the producti ...


17
Edgar C Boedeker, Frederick J Cassels, Daniel L Jarboe, Robert H Reid: Oral-intestinal vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres. Nash & Titus, March 25, 2010: US20100074913-A1

This invention is directed to oral-intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.


18

19
Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Martin Karl Russel Burnham, Robert H Reid Jr, Phillip N Zarfos: Polynucleotides encoding a novel glutamine transport ATP-binding protein. SmithKline Beecham Corporation, SmithKline Beecham, February 12, 2002: US06346392

The invention provides Glutamine Transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Glutamine Transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Glutamine Transport ATP-Binding Prote ...


20
Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Robert H Reid, Martin Rosenberg, Phillip Zarfos: Polynucleotides encoding a novel era polypeptide. SmithKline Beecham Corporation, SmithKline Beecham, Edward R Gimmi, Thomas S Deibert, William T King, September 11, 2001: US06287803

The invention provides era polypeptides and DNA (RNA) encoding era polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing era polypeptides to screen for antibacterial compounds.