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Stéphane De Lombaert
BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M: INHIBITEURS OXADIAZOLE DE PRODUCTION DE LEUCOTRIÈNES, OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M, MORRIS Michael P, March 29, 2012: WO/2012/040137

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases an ...


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Zindell Renee M, Riether Doris, Thomson David S, Wu Lifen: Compounds which modulate the cb2 receptor. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Zindell Renee M, Riether Doris, Thomson David S, Wu Lifen, MORRIS Michael P, October 18, 2007: WO/2007/118041 (22 worldwide citation)

Compounds are provided which bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, the compounds having the general formula (I) wherein R¿1?, R¿2?, R¿3?, X and Ar have the meanings given in the specification, and the preparation and use thereof. The compounds are valuable CB ...


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RIETHER DORIS: Tetrazole compounds which selectively modulate the cb2 receptor. BOEHRINGER INGELHEIM INTERNATIONAL, Morris Michael P, September 9, 2011: WO/2011/109324 (17 worldwide citation)

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.


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Riether Doris, Thomson David S, Zindell Renee: Polycyclic compounds which modulate the cb2 receptor. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Riether Doris, Thomson David S, Zindell Renee, MORRIS Michael P, April 24, 2008: WO/2008/048914 (6 worldwide citation)

Compounds of formula (I) are disclosed. Compounds according to the invention are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.


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Cirillo Pier Francesco, Thomson David S, Riether Doris, Berry Angela, Wu Lifen, Hickey Eugene Richard: Compounds which modulate the cb2 receptor. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Cirillo Pier Francesco, Thomson David S, Riether Doris, Berry Angela, Wu Lifen, Hickey Eugene Richard, MORRIS Michael P, May 29, 2008: WO/2008/064054 (6 worldwide citation)

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.