1
Richard L Kronenthal, Matthew H Wykoff: Surgical method. Ethicon, Wayne R Eberhardt, February 8, 1977: US04006747 (569 worldwide citation)

A method for closing wounds and surgical incisions in mammalian tissue which comprises fastening an approximated wound or incision with a series of devices comprising a short filament with a head on each end, each device being surgically placed so that the filament traverses the wound or incision wi ...


2
Richard L Kronenthal, Frank V Mattei, Alan J Levy: Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition. Ethicon, Leonard Kean, February 4, 1986: US04568536 (112 worldwide citation)

An absorbable biologically compatible putty-like composition is used as a matrix from which immunologically or pharmacologically active agents, such as antibiotics, can be introduced into the body to provide a slow sustained release of the agent over an extended period of time. A preferred matrix co ...


3
Richard L Kronenthal: Glass-filled, absorbable surgical devices. Ethicon, Charles J Metz, September 23, 1986: US04612923 (112 worldwide citation)

A surgical device fabricated from a synthetic absorbable polymer containing an absorbable glass filler.


4
Richard L Kronenthal, Edgar Schipper: Surgical adhesives. Ethicon, Wayne R Eberhardt, December 7, 1976: US03995641 (98 worldwide citation)

Carbalkoxyalkyl 2-cyanoacrylates having the formula: ##STR1## wherein R is an organic radical and R' is hydrogen or methyl polymerize rapidly in the presence of moisture and are useful as adhesives. When applied as tissue adhesives in surgical applications, such carbalkoxyalkyl 2-cyanoacrylates caus ...


5
Richard L Kronenthal, Frank V Mattei, Alan Levy: Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition. Ethicon, Charles J Metz, March 17, 1987: US04650665 (81 worldwide citation)

An absorbable biologically compatible putty-like composition is used as a matrix from which immunologically or pharmacologically active agents, such as antibiotics, can be introduced into the body to provide a slow sustained release of the agent over an extended period of time. A preferred matrix co ...


6
Rao S Bezwada, Richard L Kronenthal: Random copolymers of p-dioxanone, lactide and/or glycolide as coating polymers for surgical filaments. Ethicon, December 31, 1991: US05076807 (49 worldwide citation)

Low molecular weight absorbable copolymers of p-dioxanone with lactide and/or glycolide are used as coatings for surgical filaments to improve tactile smoothness and tie-down properties. These copolymers are prepared by reacting p-dioxanone with lactide and/or glycolide in the presence of an initiat ...


7
W James Huang, Douglas B Johns, Richard L Kronenthal: Ionically crosslinked carboxyl-containing polysaccharides for adhesion prevention. Lifecore Biomedical, Vidas Arrett & Steinkraus, July 2, 1996: US05532221 (36 worldwide citation)

A method of reducing post-operative adhesion formation by topically applying an ionically crosslinked carboxyl-containing polysaccharide or a pharmacologically acceptable salt thereof, e.g. sodium hyaluronate crosslinked with ferric chloride, to a site of surgical trauma.


8
Amy L Finkenaur, Jonathan M Cohen, Shalaby W Shalaby, Elisabeth A Sandoval, Rao S Bezwada, Richard L Kronenthal: Gel formulations containing growth factors and acrylamide polymer. Ethicon, June 27, 1995: US05427778 (27 worldwide citation)

Gel formulations containing polypeptide growth factors having human mitogenic or angiogenic activity are provided. The gel formulations are useful for topical or incisional wound healing for cutaneous wounds, in the anterior chamber of the eye and other ophthalmic wound healing. The gel formulations ...


9
Richard L Kronenthal, Arthur A Gertzman, Douglas R Valentine: Flexible stranded sponge pack. Xomed Surgical Products, May 26, 1998: US05755706 (20 worldwide citation)

A surgical sponge device comprising a porous cellular absorbent sponge which is cut into rigid segments. The segments are slidably mounted on a strand with a stop to keep the segments from falling off of said strand. The strung segments may be covered by a fluid impervious sleeve which, when removed ...


10
Bruce W Miller, Richard L Kronenthal: Topical composition enhancing healing of viral lesions. ViroTex Corporation, Arnold White & Durkee, January 10, 1995: US05380754 (6 worldwide citation)

Multiple daily applications of a topical composition having as the active ingredients an anesthetic and a surfactant with anti-vital activity decrease the time of healing of herpes simplex viral lesions from approximately seven to ten days to five to six days, as well as decrease inflammation and pa ...