1
Jeffrey C Felt, Mark A Rydell, Richard J Zdrahala, Alexander Arsenyev: Mold apparatus and kit for in situ tissue repair. Disc Dynamics, Fredrikson & Byron P A, September 3, 2002: US06443988 (553 worldwide citation)

A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable ...


2
Jeffrey C Felt, Mark A Rydell, Richard J Zdrahala, Alexander Arsenyev: Biomaterial system for in situ tissue repair. Advanced Bio Surfaces, Fredrikson & Byron P A, October 23, 2001: US06306177 (348 worldwide citation)

A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable ...


3
Jeffrey C Felt, Mark A Rydell, Richard J Zdrahala, Alexander Arsenyev: Biomaterial for in situ tissue repair. Advanced Bio Surfaces, Fredrikson & Byron P A, October 31, 2000: US06140452 (296 worldwide citation)

A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable ...


4
Kevin Weadock, David J Lentz, Richard J Zdrahala: Tubular expanded polytetrafluoroethylene implantable prostheses. Meadox Medicals, Hoffmann & Baron, September 9, 1997: US05665114 (152 worldwide citation)

An implantable prosthesis comprising an expanded polytetraethylene member having pores present in its wall structure wherein said pores contain a solid insoluble biocompatible, biodegradable material of natural origin. A process of preparing said prostheses is also disclosed.


5
Birendra K Patnaik, Richard J Zdrahala: Polyurethanes grafted with polyethylene oxide chains containing covalently bonded heparin. Meadox Medicals, Hoffmann & Baron, January 5, 1999: US05855618 (142 worldwide citation)

Disclosed are bio-active polymer coatings. More particularly, improved bio-active polymer coating are disclosed which include bio-active molecules attached to polyurethane backbones via amine-terminated spacers. Also disclosed are novel reaction schemes for producing same.


6
Birendra K Patnaik, Richard J Zdrahala: Process for preparing polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active agents. Meadox Medicals, Hoffmann & Baron, March 2, 1999: US05877263 (136 worldwide citation)

Disclosed are bio-active coating compositions for polymeric substrates. In particular, a bio-active coating is described which is the reaction product formed by providing a polymer backbone with at least one free isocyanate group, wherein the isocyanate group is pendant from the polymer backbone. Th ...


7
Ellen Golds, David J Lentz, Jamie Henderson, Edward J Dormier, Richard J Zdrahala: PTFE vascular prosthesis and method of manufacture. Meadox Medicals, Hoffmann & Baron, December 14, 1999: US06001125 (134 worldwide citation)

An implantable microporous ePTFE tubular vascular graft exhibits long term patency, superior radial tensile strength and suture hole elongation resistance. The graft includes a first ePTFE tube and a second ePTFE tube circumferentially disposed over the first tube. The first ePTFE tube exhibits a po ...


8
David J Lentz, Jamie Henderson, Edward J Dormier, Richard J Zdrahala: PTFE vascular graft. Meadox Medicals, Hoffmann & Baron, September 1, 1998: US05800512 (132 worldwide citation)

An implantable microporous ePTFE tubular vascular graft exhibits long term patency, superior radial tensile strength and suture hole elongation resistance. The graft includes a first ePTFE tube and a second ePTFE tube circumferentially disposed over the first tube. The first ePTFE tube exhibits a po ...


9
Birendra K Patnaik, Richard J Zdrahala: Polymer coatings grafted with polyethylene oxide chains containing covalently bonded bio-active agents. Scimed Life Systems, Hoffmann & Baron, August 22, 2000: US06107416 (130 worldwide citation)

Disclosed are bio-active coating compositions for polymeric substrates. In particular, a bio-active coating is described which is the reaction product formed by providing a polymer backbone with at least one free isocyanate group, wherein the isocyanate group is pendant from the polymer backbone. Th ...


10
Richard J Zdrahala: Extruded tubing and catheters having helical liquid crystal fibrils. Cordis Corporation, Gerstman & Ellis, September 28, 1993: US05248305 (110 worldwide citation)

Extruded catheters and other flexible plastic tubing may be manufactured with improved rotational and/or longitudinal stiffness, compared with catheters made of more conventional plastics. A tubing of liquid crystal polymer plastic-containing material may be extruded through a tube extrusion die whi ...