1
Richard J Whitbourne, Xianping Zhang: Adherent, flexible hydrogel and medicated coatings. STS Biopolymers, Michael A Venable Gollin, August 29, 2000: US06110483 (360 worldwide citation)

The adherent coating of the invention comprises a stabilizing polymer together with an active agent (a hydrophilic polymer and/or a bioactive agent) in a layer bonded to the surface of a medical device. This invention encompasses the coating liquids used for coating medical devices, methods of coati ...


2
Richard J Whitbourne: Bonding layers for medical device surface coatings. STS Biopolymers, Michael A Venable Gollin, December 7, 1999: US05997517 (359 worldwide citation)

A medical device is coated with a thin coherent bond coat of acrylics, epoxies, acetals, ethylene copolymers, vinyl polymers, polymers containing hydroxyl, amine, carboxyl, amide, or other reactive groups, and copolymers thereof. Outer layers may be applied and remain adherent to the substrate in wa ...


3
Richard J Whitbourne: Bonding layers for medical device surface coatings. STS Biopolymers, Michael A Gollin, Venable, October 23, 2001: US06306176 (301 worldwide citation)

The medical device is coated with a thin coherent bond coat of acrylics, epoxies, acetals, ethylene copolymers, vinyl polymers containing hydroxyl, amine, carboxyl, amide or other reactive groups, and copolymers thereof. Outer layers may be applied and remain adherent to the substrate in water for a ...


4
Michael R Violante, Richard J Whitbourne, John F Lanzafame, Margaret Lydon: Echogenic coatings. STS Biopolymers, Michael A Venable Gollin, August 22, 2000: US06106473 (230 worldwide citation)

Coatings to enhance the echogenicity of materials are especially useful for medical devices wherein the practitioner desires to locate or visualize a device by ultrasonic imaging when the device is inserted into a body cavity. These coatings can be applied to any device of virtually any composition. ...


5
Richard J Whitbourne, Margaret A Mangan: Coating compositions comprising pharmaceutical agents. STS Biopolymers, Michael A Gollin, June 11, 1996: US05525348 (99 worldwide citation)

Anti-thrombogenic, and/or anti-microbial and/or pharmaceutical compositions containing heparin and/or antibiotics and/or other pharmaceutical agents which may be reacted with quaternary ammonium components or other ionic surfactants and bound with water-insoluble polymers are disclosed. Such composi ...


6
Richard J Whitbourne: Lubricious hydrophilic coating, resistant to wet abrasion. Sterilization Technical Services, Kenyon & Kenyon, July 19, 1994: US05331027 (94 worldwide citation)

The lubricious hydrophilic coatings of the invention are significantly more lubricious when wet than when dry, are adherent to a variety of substrates, and are resistant to removal by wet abrasion. In one embodiment, the coatings include a hydrophilic polyolefin such as polyvinyl-pyrrolidone and a w ...


7
Richard J Whitbourne: Lubricious hydrophilic composite coated on substrates. Sterilization Technical Services, Kenyon & Kenyon, March 19, 1991: US05001009 (82 worldwide citation)

The lubricious hydrophilic coatings of the invention include a hydrophilic polyolefin such as polyvinyl-pyrrolidone and a water-insoluble stabilizing polymer such as a cellulose ester. The coatings may also include an adherent polymer and a plasticizing agent. The coatings are significantly more lub ...


8
Xianping Zhang, Richard J Whitbourne: Hydrophilic coatings with hydrating agents. STS Biopolymers, Spencer & Frank, September 1, 1998: US05800412 (73 worldwide citation)

According to the invention, hydrating agents in ultrafine form may be incorporated in an organic coating solution with a uniform distribution that does not change due to settling. In preferred embodiments, the coating solution comprises salt dissolved in an appropriate organic solvent blend. In anot ...


9
Richard J Whitbourne, Margaret A Mangan: Anti-thrombogenic, anti-microbial compositions containing heparin. Sterilization Technical Services, Marjama & Pincelli, December 3, 1991: US05069899 (38 worldwide citation)

Anti-thrombobenic, anti-microbial compositions containing heparin reacted with quaternary ammonium components and bound with water-insoluble polymers are disclosed. Such compositions may also contain additional quaternary ammonium compounds not reacted with heparin and may also contain quaternary am ...


10
Michael R Violante, Richard J Whitbourne, John F Lanzafame, Margaret Lydon: Echogenic coatings with overcoat. Angiotech Biocoatings, Venable, Michael A Gollin, Zayd Alathari, June 12, 2007: US07229413 (26 worldwide citation)

An ultrasonically visible solid device for inserting into a non-gas target medium comprises an echogenic surface having structures entrapping gas when the device is in the target medium, the entrapped gas causing the device to be ultrasonically visible, wherein the gas-entrapping structures are cove ...