1
Kary B Mullis, Larry Johnson, Richard A Leath, Timothy J Wennberg, Louis M Mezei, Joseph T Widunas: System for automated performance of the polymerase chain reaction. The Perkin Elmer Corporation, William J Hone, Richard P Ferrara, August 12, 1997: US05656493 (315 worldwide citation)

There is disclosed herein a machine for performing nucleic acid amplification under computer control. The machine utilizes any one of a number of heating and cooling systems under control of a host computer which directs the heating and cooling systems to heat and cool a reaction-chamber-containing ...


2
Kary B Mullis, Larry Johnson, Richard A Leath, Timothy J Wennberg, Louis M Mezei, Joseph T Widunas: Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps. Hoffmann La Roche, Davis Hoxie Faithfull & Hapgood, August 2, 1994: US05333675 (176 worldwide citation)

There is disclosed herein a machine for performing nucleic acid amplification under computer control. The machine utilizes any one of a number of heating and cooling systems under control of a host computer which directs the heating and cooling systems to heat and cool a reaction-chamber-containing ...


3
Louis M Mezei, Richard W Reeves, Richard A Leath, Joseph T Widunas: Liquid handling device and method. Cetus Corporation, Albert P Halluin, Peter J Dehlinger, Ronald C Fish, May 6, 1986: US04586546 (111 worldwide citation)

An improved liquid handling device used for transferring a selected quantity of liquid from one receptacle to another. The device includes a meniscus tracking feature which minimizes mixing in a liquid sample and contact between the sample and a sample-handling pipette during a liquid-transfer opera ...