1
Lonetto Michael A, Jaworski Deborah D, Wang Min, Kosmatka Anna L, Black Michael T, Reid Robert H, Zarfos Phillip, Hodgson John E, Knowles David J C: Def2 protein from streptococcus pneumoniae. Smithkline Beecham, Smithkline Beecham, September 9, 1998: EP0863205-A1 (2 worldwide citation)

The invention provides def2 polypeptides and polynucleotides encoding def2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def2 polypeptides to screen for antibacterial compounds.


2
Jeyanthi Ramasubbu, Van Hamont John F, Friden Phil, Reid Robert H, Roberts F Donald, Mcqueen Charles E, Setterstrom Jean A: Novel "burst-free" sustained release poly-(lactide/glycolide) mi crospheres. US Army, January 14, 1998: EP0817619-A1

Novel burst-free, sustained release biocompatible and biodegradable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologicall ...


3
Reid Robert H, Boedeker Edgar C: Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.. Us Government, November 15, 1995: EP0681478-A1

This invention is directed to oral parenteral and intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.


4
Jeyanthi Ramasubbu, Van Hamont John F, Friden Phil, Reid Robert H, Roberts F Donald, Mcqueen Charles E, Setterstrom Jean A: Microspheres nouvelles en poly-(lactide-glycolide) a liberation controle� a lepreuve de leclatement �, Novel "burst-free" sustained release poly-(lactide/glycolide) microspheres. United States Government Represented By The Secretary Of The Army, United States Government Represented By The Secretary Of The Army, RIDOUT & MAYBEE, July 31, 1997: CA2216371

Novel burst-free, sustained release biocompatible and biodegradable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologicall ...


5
Black Michael Terence, Hodgson John Edward, Knowles David Justin Charles, Lonetto Michael Arthur, Nicholas Richard Oakley, Reid Robert H Jr, Zarfos Philip N: Novel bacterial polypeptides and polynucleotides. Smithkline Beecham, Smithkline Beecham, August 2, 2000: EP1023311-A1

This invention relates to newly identified Streptococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polyucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells tranformed with the polynucleotides. ...


6
Black Michael Terence, Hodgson John Edward, Knowles David Justin Charles, Lonetto Michael Arthur, Nicholas Richard Oakley, Reid Robert H Jr, Zarfos Philip N: Novel bacterial polypeptides and polynucleotides. Smithkline Beecham Corporation, Smithkline Beecham, Black Michael Terence, Hodgson John Edward, Knowles David Justin Charles, Lonetto Michael Arthur, Nicholas Richard Oakley, Reid Robert H Jr, Zarfos Philip N, GIMMI Edward R, June 4, 1998: WO/1998/023631

This invention relates to newly identified Streptococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polyucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells tranformed with the polynucleotides. ...


7
Black Michael Terance, Hodgson John Edward, Knowles David Justin Charles, Lonetto Michael Arthur, Nicholas Richard Oakley, Reid Robert H Jr, Zarfos Phillip N: Novel coding sequences. Smithkline Beecham Corporation, Smithkline Beecham, Black Michael Terance, Hodgson John Edward, Knowles David Justin Charles, Lonetto Michael Arthur, Nicholas Richard Oakley, Reid Robert H Jr, Zarfos Phillip N, GIMMI Edward R, May 14, 1998: WO/1998/019689

This invention relates to newly identified Streptococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotide ...


8
Reid Robert H, Sadegh Nasseri Scheherazade, Wolff Marcia, Nauss Jeffrey L: Model for testing immunogenicity of peptides. United States Of, America Represented By, The Secretary Of The Army, Reid Robert H, Sadegh Nasseri Scheherazade, Wolff Marcia, Nauss Jeffrey L, NORRIS Jerome J, November 30, 1995: WO/1995/031997

Assay methods for determining whether a peptide is likely to be immunogenic are based on a computer modeling of binding to a Class II MHC DR1 receptor. This is confirmed by competitive inhibition binding assays. The peptides are useful for eliciting an immune response for vaccination or the producti ...


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Reid Robert H, Boedeker Edgar C: Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres. The United States Of, America Represented By, The Secreraty Of The Army, Reid Robert H, Boedeker Edgar C, BELLAMY Werten F W, September 29, 1994: WO/1994/021289

This invention is directed to oral parenteral and intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.