1
Rusch Volker Dipl Biol Dr Rer, Reichhart Robert Dipl Chem, Zeppezauer Michael Prof Dr Rer, Jornvall Hans Prof Dr: Biologically active substance with hormonal characteristics, process for its preparation and use of histons for medicinal ends.. Rusch Volker, July 24, 1985: EP0149468-A2 (5 worldwide citation)

The invention relates to the use of pure histones H1, or the histone dimer H2A:H2B for therapeutic procedures. Instead of the pure histones active segments thereof with hormone or hormone like activity especially thymic hormone like activity can be used alone or in combination with the pure histones ...


2
Zeppezauer Michael, Reichhart Robert: Pure histone h1 for use in therapeutic procedures.. Symbiotec, October 17, 1990: EP0392315-A1 (5 worldwide citation)

The invention relates to the use of pure histones H1, or the histone dimer H2A:H2B for therapeutic procedures. Instead of the pure histones active segments thereof with hormone or hormone like activity especially thymic hormone like activity can be used alone or in combination with the pure histones ...


3
Reichhart Robert, Jornvall Hans, Rusch Volker, Zeppezauer Michael: Substance biologiquement active ayant des proprietes hormonales, prodede de production et application dhistones a des fins medicales, Biologically active substance with hormonal properties, process for its production and application of histones for medical purposes. Volker Rusch, OGILVY RENAULT SENCRLSRL, March 14, 1989: CA1251134

ABSTRACT OF THE DISCLOSURE A biologically active substance with standardized effect isproposed, containing in a physiological medium at least onehistone, particularly an H2 histone or an active region of thishistone. The use of histones and/or histone segments forproducing such a preparation is also ...


4
Rusch Volker, Reichhart Robert, Zeppezauer Michael, Jörnvall Hans: Biologically active substance with hormonal properties, production process thereof and utilization of histones for medical purposes. Rusch Volker, Reichhart Robert, Zeppezauer Michael, Jörnvall Hans, PÄTZOLD Herbert, July 18, 1985: WO/1985/003003

Biologically active substance with standardizable hormonal activity, containing in a physiological medium at least one histone, particularly at least one histone H2 or an active area of said histone with immune system immunostimulating and/or endocrinological properties. Utilization of histones and/ ...



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