1
Keith L March, Michael Aita, Randy Kesten, Craig Smith: Therapeutic and diagnostic agent delivery. CardioGenesis Corporation, Indiana University Foundation, Columbia University, Heller Ehrman White McAuliffe, November 24, 1998: US05840059 (169 worldwide citation)

A system for treating a patient's heart which comprises a means to form channels in the heart wall and a means to deliver a therapeutic or diagnostic agent into the channels. Additionally, the system may comprise a way to retain the agent within the channels for a useful period of time. The system m ...


2
Keith L March, Michael Aita, Randy Kesten, Craig Smith: Therapeutic and diagnostic agent delivery. Cardiogenesis Corporation, Heller Ehrman White & McAuliffe, December 7, 1999: US05997525 (81 worldwide citation)

A system for treating a patient's heart which comprises a means to form channels in the heart wall and a means to deliver a therapeutic or diagnostic agent into the channels. Additionally, the system may comprise a means to retain the agent within the channels for a useful period of time. The system ...


3
Keith L March, Michael Aita, Randy Kesten, Craig Smith: Therapeutic and diagnostic agent delivery. Eclipse Surgical Technologies, Edward J Lynch, Ilene L Janofsky, Ross M Carothers, May 1, 2001: US06224584 (63 worldwide citation)

A system for treating a patient's heart which comprises a means to form channels in the heart wall and a means to deliver a therapeutic or diagnostic agent into the channels. Additionally, the system may comprise a means to retain the agent within the channels for a useful period of time. The s ...


4
Gad Keren, Randy Kesten: Methods and apparatus for reducing localized circulatory system pressure. V Wave, Jones Day, Nicola A Pisano, Jaime D Choi, January 10, 2012: US08091556 (21 worldwide citation)

Methods and apparatus for decreasing cardiac pressure in a patient by implanting a shunt communicating with an area outside a first portion, whereby a volume of blood sufficient to reduce pressure in a first portion is released. Preferably, the end diastolic pressure in the left ventricle is reduced ...


5
Gad Keren, Randy Kesten: Methods and apparatus for reducing localized circulatory system pressure. V Wave, Jones Day, Nicola A Pisano, Jaime D Choi, August 7, 2012: US08235933 (14 worldwide citation)

The present invention is directed to methods and apparatus for decreasing pressure in the left atrium of a patient by implanting a valved shunt through the atrial septum, whereby a volume of blood sufficient to reduce pressure in said left atrium is released to the right atrium.


6
Gad Keren, Randy Kesten: Methods and apparatus for reducing localized circulatory system pressure. V Wave, Jones Day, Nicola A Pisano, Jaime D Choi, December 11, 2012: US08328751 (8 worldwide citation)

The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said fi ...


7
Keith L March, Michael Aita, Randy Kesten, Craig Smith: Therapeutic and diagnostic agent delivery. CardioGenesis Corporation, Gibson Dunn & Crutcher, February 25, 2003: US06524298 (1 worldwide citation)

A system for treating a patient's heart which comprises a means to form channels in the heart wall and a means to deliver a therapeutic or diagnostic agent into the channels. Additionally, the system may comprise a means to retain the agent within the channels for a useful period of time. The s ...


8
Gad Keren, Randy Kesten: Methods and apparatus for reducing localized circulatory system pressure. V Wave, Foley & Lardner, Christopher C Bolten, Nicola A Pisano, April 17, 2018: US09943670

The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said fi ...


9
Matthew J Stepovich, Randy Kesten, Jeff Zalewski: Apparatus and methods for sequestering fluids exhausted during fluid transfer. ONPHARMA, Thompson Hine, November 15, 2016: US09492351

A liquid transfer connector comprises an enclosure holding a transfer needle and an exhaust needle. A container of donor liquid may be attached to an inlet end of the transfer needle and a container holding a recipient liquid may be attached to an outlet end of the transfer needle and an inlet end o ...


10
Gad Keren, Randy Kesten: Methods and apparatus for reducing localized circulatory system pressure. Schnader Harrison Segal & Lewis, November 21, 2002: US20020173742-A1

The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said fi ...