1
Richard D Antanavich, Randel Dorian: Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant. PlasmaSeal Corporation, William B Walker, December 17, 1996: US05585007 (201 worldwide citation)

An inexpensive device with a disposable cartridge for preparing tissue sealant is disclosed. The device is particularly applicable to star preparation of autologous tissue sealant. A method of sealing tissue in which the tissue sealant is applied immediately after mixing platelet-rich plasma concent ...


2
Randel Dorian, Richard Wood Storrs: Plasma concentrate apparatus and method. Hanuman, William B Walker, June 14, 2005: US06905612 (164 worldwide citation)

A plasma concentrator for producing plasma concentrate from a plasma from which erythrocytes have been substantially removed. The device comprises a concentrating chamber having an inlet port and an concentrate outlet, the concentrating chamber containing hydrogel beads and at least one inert agitat ...


3
Richard D Antanavich, Randel Dorian: Methods for making concentrated plasma and/or tissue sealant. Plasmaseal, William B Walker, August 4, 1998: US05788662 (153 worldwide citation)

An inexpensive device with a disposable cartridge for preparing tissue sealant is disclosed. The device is particularly applicable to stat preparation of autologous tissue sealant. A method of sealing tissue in which the tissue sealant is applied immediately after mixing platelet-rich plasma concent ...


4
Richard D Antanavich, Randel Dorian: Method and apparatus for applying tissue sealant. Plasmaseal, William B Walker, September 29, 1998: US05814022 (132 worldwide citation)

A device and method for applying a fibrinogen-based tissue sealant to seamlessly connect human or animal tissues or organ parts, to seal wounds, stop bleeding and the like by mixing fibrin or fibrinogen with blood clot-promoting coagulation factors are disclosed. The device includes two cylindrical ...


5
Richard D Antanavich, Randel Dorian: Method and apparatus for making concentrated plasma and/or tissue sealant. PlasmaSeal, Edward N Flehr Hohbach Test Albritton & Herbert Bachand, May 16, 2000: US06063297 (124 worldwide citation)

An inexpensive device with a disposable cartridge for preparing tissue sealant is disclosed. The device is particularly applicable to stat preparation of autologous tissue sealant. A method of sealing tissue in which the tissue sealant is applied immediately after mixing platelet-rich plasma concent ...


6
Richard D Antanavich, Randel Dorian: Plasma concentrate and method of processing blood for same. Plasmaseal, Flehr Hohbach Test Albritton & Herbert, April 10, 2001: US06214338 (116 worldwide citation)

A plasma concentrate comprising one of platelets and platelet releasate and from 5 to 400 mg/ml of fibrinogen. The concentrate further includes a physiologically acceptable carrier comprising water and physiologically acceptable inorganic and organic ions at a physiologically acceptable concentratio ...


7
Richard D Antanavich, Randel Dorian: Apparatus for applying tissue sealant. PlasmaSeal, Flehr Hohbach Test Albritton & Herbert, October 17, 2000: US06132396 (116 worldwide citation)

A device and method for applying a fibrinogen-based tissue sealant to seamlessly connect human or animal tissues or organ parts, to seal wounds, stop bleeding and the like by mixing fibrin or fibrinogen with blood clot-promoting coagulation factors are disclosed. The device includes two cylindrical ...


8
Randel Dorian, Scott R King, Richard Wood Storrs: Methods and apparatus for isolating platelets from blood. Hanuman, William B Walker, May 29, 2007: US07223346 (88 worldwide citation)

A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the den ...


9
Randel Dorian, Scott R King, Richard Wood Storrs: Methods and apparatus for isolating platelets from blood. Hanuman, Harness Dickey & Pierce, December 30, 2008: US07470371 (79 worldwide citation)

A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the den ...


10
Richard D Antanavich, Randel Dorian: RETRIEVABLE BIOARTIFICIAL IMPLANTS HAVING DIMENSIONS ALLOWING RAPID DIFFUSION OF OXYGEN AND RAPID BIOLOGICAL RESPONSE TO PHYSIOLOGICAL CHANGE, PROCESSES FOR THEIR MANUFACTURE, AND METHODS FOR THEIR USE. Islet Sheet Medical, David J Brezner, Flehr Hohbach Test Albritton & Herbert, April 16, 2002: US06372244 (79 worldwide citation)

Bioartificial implants and methods for their manufacture and use are described, particularly bioartificial pancreases. In particular, the implants may be thin sheets which enclose cells, may be completely biocompatible over extended periods of time and may not induce fibrosis. The high-density-cell- ...