1
Randall T Sparks, Edward J Geoghegan: Controlled release powder and process for its preparation. Elan Corporation, Marla J Church, October 11, 1994: US05354556 (427 worldwide citation)

A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an ...


2
Randall T Sparks, Edward J Geoghegan: Controlled release powder and process for its preparation. Elan Corporation, Robert Hardy Falk, Henry Croskell, August 28, 1990: US04952402 (227 worldwide citation)

A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an ...


3
Randall T Sparks, Edward J Geoghegan: Controlled release powder and process for its preparation. Elan Corporation, Robert H Falk, Henry Croskell, July 10, 1990: US04940588 (156 worldwide citation)

A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an ...


4
Seamus Mulligan, Randall T Sparks: Drug delivery system. Elan Corporation, Marla J Church, November 27, 1990: US04973469 (64 worldwide citation)

A controlled release formulation comprising an adsorbate of a mixture of a pharmaceutically useful active ingredient and an inactive substance adsorbed on a cross-linked polymer. The inactive substance is selected to modify the dissolution of the active ingredient from the cross-linked polymer in vi ...


5
Seamus Mulligan, Randall T Sparks: Sustained release drug delivery system. Elan Corporation, Church Marla J, July 7, 1992: US05128142 (42 worldwide citation)

A controlled release formulation comprising an adsorbate of a mixture of a pharmaceutically useful active ingredient and an inactive substance adsorbed on a cross-linked polymer. The inactive substance is selected to modify the dissolution of the active ingredient from the cross-linked polymer in vi ...


6
Seamus Mulligan, Randall T Sparks: Sustained release capsule or tablet formulation comprising a pharmaceutically acceptable dihydropyridine. May 14, 1991: US05015479 (39 worldwide citation)

A sustained release capsule or tablet formulation suitable for once-daily administration comprises an adsorbate of a mixture of a pharmaceutically useful dihydropyridine and a polyvinylpyrrolidone having an average-molecular weight greater than 55,000 adsorbed on a cross-linked polyvinylpyrrolidone ...


7
Randall T Sparks: Controlled release pharmaceutical formulation. Elan Corporation, Mary L Severson, April 9, 1996: US05505962 (24 worldwide citation)

An improved controlled release tablet formulation for the release of potassium chloride through a differentially permeable membrane from which the release of potassium chloride can be accurately controlled to minimize the likelihood of producing high localized concentrations of potassium within the ...