1
Peter P Speiser, Rajendra K Joshi: Pharmaceutical composition and process for the production thereof. Cohen Pontani Lieberman Pavane, June 13, 1995: US05424332 (45 worldwide citation)

A pharmaceutical composition in dosage form for treating psoriasis and psoriatic arthritis includes, essentailly, as active substance (s), a fumaric acid monoalkylester salt having the formula ##STR1## wherein R is a methyl, propyl or isopropyl group, and M.sup.++ is calcium, alone or in combination ...


2
Peter P Speiser, Rajendra K Joshi: Fumaric acid derivatives, process for the production thereof and pharmaceutical compositions containing same. Cohen Pontani & Lieberman, July 25, 1989: US04851439 (38 worldwide citation)

Fumaric acid derivatives of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.8 alkyl group or a metallic cation, and


3
Peter P Speiser, Rajendra K Joshi: Pharmaceutical preparation for the treatment of psoriatic arthritis. Cohen Pontani & Lieberman, September 25, 1990: US04959389 (36 worldwide citation)

A composition including at least one salt of fumaric acid monoalkyl ester having the formula: ##STR1## alone or in combination with dialkyl fumarate having the formula: ##STR2## is provided for treatment of psoriasis and psoriatic arthritis. In particular, use of the calcium salt of fumaric acid mon ...


4
Peter P Speiser, Rajendra K Joshi: Fumaric acid derivatives, process for the production thereof and pharmaceutical compositions containing same. Cohen Pontani Lieberman Pavane, September 19, 1995: US05451667 (35 worldwide citation)

Fumaric acid derivatives of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.8 alkyl group or a metallic cation, and


5
Peter P Speiser, Rajendra K Joshi: Fumaric acid derivatives, process for the production thereof and pharmaceutical compositions containing same. Cohen Pontani Lieberman & Pavane, September 22, 1992: US05149695 (34 worldwide citation)

Fumaric acid derivatives of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.8 alkyl group or a metallic cation, and


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Rajendra K Joshi, Hans Peter Strebel: Use of fumaric acid derivatives. Fumapharm, guo xiaodong, June 21, 2000: CN98805308

The invention relates to the use of given fumaric acid monoalkyl esters as salts or free acids either alone or combined with a dyakyl fumarate in the production of pharmaceutical preparations for the treatment of polyarthritis or multiple sclerosis, in addition to graft-versus-host reaction.


8
Rajendra K Joshi, Hans Peter Strebel: Utilization of alkyl hydrogen fumerates for treating psoriasis, psoriatic arthritis, neurodermatitis and regional enteritis. Fumapharm, guo xiaodong, February 21, 2001: CN98813834

The invention relates to the use of one or several alkyl hydrogen fumarates of the general formula wherein R is a C1-5 alkyl, optionally in admixture with dialkyl fumarate of the formula and optionally customary pharmaceutical excipients and carriers for preparing a pharmaceutical composition in the ...


9
Rajendra K Joshi, Hans Peter Strebel, Christian Zaugg, Michael Tamm: Use of fumaric acid derivatives for treating cardiac insufficiency, and asthma. Fumapham, Patent & Trademark Coordinator, Legal Department, February 1, 2007: US20070027076-A1

According to a first aspect the invention relates to the use of fumaric acid derivatives selected from the group consisting of dialkyl fumarates, monoalkyl hydrogen fumarates, fumaric acid monoalkyl ester salts, fumaric acid monoamides, monoamido fumaric acid salts, fumaric acid diamides, monoalkyl ...


10
Rajendra K Joshi, Hans Peter Strebel: Carbocyclic and oxacarbocyclic fumaric acid oligomers. Sieberth & Patty, July 7, 2005: US20050148664-A1

The present invention relates to certain carbocyclic and oxacarbocyclic fumaric acid oligomers and the use thereof for preparing a pharmaceutical preparation as well of pharmaceutical preparations containing these compounds.