1
Rainer Alex, Paul Hadvary, Hansjorg Tschirky: Dermally affixed injection device. Hoffmann La Roche, George W Johnston, William H Epstein, John P Parise, August 3, 1999: US05931814 (484 worldwide citation)

An improved injection device has a casing containing an active substance reservoir, a cannula communicating with the reservoir, a device for inserting the cannula, and pump means for discharging the reservoir contents through the cannula. The cannula 11 is fixed relative to the casing and projects b ...


2
Rainer Alex, Jürgen Gerhards, Ingeborg Kraemer Pittrof, Richard Oeschger, Thomas Rades: Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses. Hoffman La Roche, George W Johnston, Patricia S Rocha Tramaloni, Eileen M Ebel, March 5, 2002: US06352717 (2 worldwide citation)

The present invention provides a process for encapsulating a shear sensitive fill mass which contains a pharmaceutical active agent or nutrient, characterized in that said fill mass is heated and subsequently cooled, prior to the encapsulation. The invention also provides capsules comprising shear s ...


3
Rainer Alex, Paulhadvary, Hansjorg Tschirky: Injection device injektionsvorrichtung. F Hoffmann La Roche, LIU ZHIPING, July 31, 1996: CN95117668

An improved injection device has a casing containing an active substance reservoir, a cannula communicating with the reservoir, a device for inserting the cannula, and pump means for discharging the reservoir contents through the cannula. The cannula 11 is fixed relative to the casing and projects b ...


4
Rainer Alex, Jurgen Gerhards, Ingeborg Kraemer Pittrof, Richard Oeschger, Thomas Rades: Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses. Hoffmann La Roche, Hoffmann La Roche, Patent Law Department, January 17, 2002: US20020006417-A1

The present invention provides a process for encapsulating a shear sensitive fill mass which contains a pharmaceutical active agent or nutrient, characterised in that said fill mass is heated and subsequently cooled, prior to the encapsulation. The invention also provides capsules comprising shear s ...


5
Rainer Alex, Benno Rothenhaeusler: Solid dosage form. Hoffmann La Roche, Patent Law Department, July 28, 2005: US20050163866-A1

A solid dosage form (1) which comprises a predefined magnetic pattern (2), representing information. The dosage form (1) may be an oral dosage form such as a tablet or a capsule, and the magnetic pattern (2) may be invisible. The information contained in the magnetic pattern (2) may be coded.


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