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Robert Edward Babine, Shu Hui Chen, Ivan Collado, Cristina Garcia Paredes, John Irvin Glass, Deqi Guo, Ling Jin, Jason Eric Lamar, Raymond Samuel Parker III, Nancy June Snyder, Xicheng David Sun, Mark Joseph Tebbe, Frantz Victor, Q May Wang, Yvonne Yee Mai Yip, Robert B Perni, Luc Farmer: Peptidomimetic protease inhibitors. Vertex Pharmaceuticals Incorporated, Honigman Miller Schwartz and Cohn, Jonathan P O Brien, Kathryn D Soulier, October 26, 2010: US07820671 (17 worldwide citation)

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The in ...


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Robert Edward Babine, Shu Hui Chen, Jason Eric Lamar, Nancy June Snyder, Xicheng Sun, Mark Joseph Tebbe, Frantz Victor, Q May Wang, Yvonne Yee Mai Yip, Ivan Collado, Cristina Garcia Paredes, Raymond Samuel Parker III, Ling Jin, Deqi Guo, John Irvin Glass: Peptidomimetic protease inhibitors. Vertex Pharmaceuticals Incorporated, Honigman Miller Schwartz and Cohn, Jonathan P O Brien, Kathryn D Soulier, August 28, 2012: US08252923 (10 worldwide citation)

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The in ...


3
Paul Luther Skatrud, Robert Brown Peery, Q May Wang, Paul Robert Rosteck Jr, Michele Louise Young Bellido: Streptococcus pneumoniae gene sequence FtsY. Eli Lilly and Company, Thomas D Webster, September 28, 1999: US05958730 (2 worldwide citation)

The invention provides isolated nucleic acid compounds encoding FtsY of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.


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Robert Edward Babine, Shu Hui Chen, Ivan Collado, Cristina Garcia Paredes, John Irvin Glass, Ling Jin, Jason Eric Lamar, Raymond Samuel Parker III, Nancy June Snyder, Xicheng David Sun, Deqi Guo, Yvonne Yee Mai Yip, Q May Wang, Frantz Victor, Mark Joseph Tebbe, Robert B Perni, Luc Farmer: Peptidomimetic protease inhibitors. Vertex Pharmaceuticals Incorporated, Honigman Miller Schwartz and Cohn, Kathryn D Soulier, Jonathan P O Brien, September 10, 2013: US08529882

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel stereoselective processes to intermediates. The i ...


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Robert Brown Peery, Paul Luther Skatrud, Q May Wang, Michele Louise Young Bellido: Strepococcus pneumoniae gene sequence FtsH. Eli Lilly and Company, Charles E Cohen, Thomas D Webster, October 24, 2000: US06136557

The invention provides isolated nucleic acid compounds encoding FtsH of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.


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Robert Edward Babine, Shu Hul Chen, Jason Eric Lamar, Nancy June Snyder, Xicheng David Sun, Mark Joseph Tebbe, Frantz Victor, Q May Wang, Yvonne Yee Mai Yip, Ivan Collado, Cristina Garcia Paredes, Raymond Samuel Parker, Ling Jing, Deqi Guo, John Irvin Glass: Peptidomimetic protease inhibitors. Eli Lilly And Company, September 8, 2005: US20050197299-A1

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The in ...


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Robert Edward Babine, Shu Hui Chen, Jason Eric Lamar, Nancy June Snyder, Xicheng Sun, Mark Joseph Tebbe, Frantz Victor, Q May Wang, Yvonne Yee Mai Yip, Ivan Collado, Cristina Garcia Paredes, Raymond Samuel Parker III, Ling Jin, Deqi Guo, John Irvin Glass: Peptidomimetic protease inhibitors. Jonathan P O Brien PhD, Honigman Miller Schwartz & Cohn, June 3, 2010: US20100137583-A1

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The in ...


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Robert Edward Babine, Shu Hui Chen, Ivan Collado, Cristina Garcia Paredes, John Irvin Glass, Deqi Guo, Ling Jin, Jason Eric Lamar, Raymond Samuel Parker Iii, Nancy June Snyder, Xicheng David Sun, Yvonne Yee Mai Yip, Q May Wang, Frantz Victor, Mark Joseph Tebbe, Robert B Perni, Luc Farmer: Peptidomimetic protease inhibitors. Vertex Pharmaceuticals Incorporated, March 15, 2012: US20120064034-A1

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The in ...