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Toumazou Christofer, Purushothaman Sunil: Qpcr using solid-state ph sensing. Dna Electronics, Toumazou Christofer, Purushothaman Sunil, IRVINE Jonquil Claire, September 12, 2008: WO/2008/107014 (103 worldwide citation)

Use of a pH sensor comprising an ion-sensitive field effect transistor (ISFET) to perform real time detection/ quantification of nucleic acid amplification, e.g. polymerase chain reaction (PCR) nucleic acid amplification, based on detection of protons released during the primer extension phase.


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Toumazou Christofer, Purushothaman Sunil: Sensing apparatus and method. Toumazou Christofer, Purushothaman Sunil, December 10, 2003: GB2389424-A (4 worldwide citation)

A sensing apparatus comprising an ion sensitive field effect transistor arranged to generate an electrical output signal in response to localised fluctuations of ionic charge at or adjacent the surface of the transistor, and means for detecting the electrical output signal from the ion sensitive fie ...


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Toumazou Christofer, Purushothaman Sunil: Apparatus and method for the detection of localised fluctuactions of ionic charge by ion sensitive field effect transistors during a chemical reaction. Toumazou Christofer, Purushothaman Sunil, ROBERTS Peter David, September 4, 2003: WO/2003/073088 (4 worldwide citation)

Sensor and method to detect localised fluctuations of ionic charge indicating events occuring during a chemical reaction, the sensing apparatus comprising an ion sensitive field effect transistor arranged to generate an electrical output signal in response to localised fluctuations of ionic charge a ...


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Toumazou Christofer, Purushothaman Sunil: Apparatus and method for the detection of localised fluctuations of ionic charge by ion sensitive field effect transistors during a chemical reaction. Toumazou Christofer, Purushothaman Sunil, January 14, 2004: EP1379863-A2

Sensor and method to detect localised fluctuations of ionic charge indicating events occuring during a chemical reaction, the sensing apparatus comprising an ion sensitive field effect transistor arranged to generate an electrical output signal in response to localised fluctuations of ionic charge a ...


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Toumazou Christofer, Purushothaman Sunil: QPCR using solid-state pH sensing. DNA Electronics, Zhou Jianqiu, Wang Fengdong, June 16, 2010: CN200780052692

Use of a pH sensor comprising an ion-sensitive field effect transistor (ISFET) to perform real time detection/ quantification of nucleic acid amplification, e.g. polymerase chain reaction (PCR) nucleic acid amplification, based on detection of protons released during the primer extension phase.