1
Jan Lewandowski, Paul S Malchesky, Yukihiko Nose: Pulse voltammetry. The Cleveland Clinic Foundation, Fay Sharpe Beall Fagan Minnich & McKee, January 30, 1990: US04897162 (345 worldwide citation)

A glucose sensing apparatus and method includes an electrocatalytic sensor having a reference electrode and a sensing electrode. A periodic signal is comprised of a ramp voltage which is intermingled a series of square wave measurement pulses. This signal is applied to the sensor. Current levels are ...


2
Paul S Malchesky, Yukihiko Nose: Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid. Japan Foundation for Artificial Organs, Baldwin Egan Walling & Fetzer, September 21, 1982: US04350156 (104 worldwide citation)

An on-line filtration system for the removal of macromolecules greater than 70,000 mol. wt. from a physiological solution, such as blood, in the therapeutic treatment of various disease states. For blood, the plasma (which contains the macromolecules) is separated continuously from the blood using a ...


3
Yukihiko Nose, Koji Kayashima, Akinori Sueoka, Yoshihiro Asanuma, Shigeru Shinagawa, James Smith, Andrej Werynski, Paul S Malchesky: Method for treating blood plasma employing a hollow fiber membrane. Kuraray, Barry Kramer, September 6, 1983: US04402940 (60 worldwide citation)

This invention provides a method for treating blood plasma wherein a hollow fiber membrane which comprises at least a skin layer on one surface of the membrane and also a porous layer inside the membrane is employed. The skin layer of the membrane has micropores with average pore size of 50 to 450 A ...


4
Paul S Malchesky: Sterilization apparatus utilizing catholyte and anolyte solutions produced by electrolysis of water. Steris Corporation, Fay Sharpe Beall Fagan Minnich & McKee, August 3, 1999: US05932171 (54 worldwide citation)

An apparatus (A) for sterilizing medical instruments and other articles includes a tray (12) with an article receiving area (14). An article to be microbially decontaminated is positioned in the receiving area (14) and a microbe blocking lid (10) is closed. A water electrolysis apparatus (30) receiv ...


5
Yukihiko Nose, Paul S Malchesky: Method for low pressure filtration of plasma from blood. Takeda Chemical, Wenderoth Lind & Ponack, May 3, 1983: US04381775 (51 worldwide citation)

A method for carrying out separation of plasma from whole blood, in which whole blood is passed through a filtration membrane means of a material suitable for separating plasma from whole blood and having a pore size from 0.1 to 0.6 microns at positive pressure differential across the membrane in a ...


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Corrie L Carnes, Kenneth J Klabunde, Olga Koper, Lisa S Martin, Kyle Knappenberger, Paul S Malchesky, Bill R Sanford: Decontaminating systems containing reactive nanoparticles and biocides. United States Air Force, December 7, 2004: US06827766 (48 worldwide citation)

Improved area decontamination products and methods of use thereof are provided which include reactive nanoparticles (e.g., metal oxides, hydroxides and mixtures thereof) with one or more biocides and a liquid carrier for the nanoparticles and biocide(s). The products may be formulated for area decon ...


8
Paul S Malchesky, Raymond C Kralovic: Controlled oxygen/anti-microbial release films. Steris Corporation, Fay Sharpe Beall Fagan Minnich & McKee, April 18, 1995: US05407685 (43 worldwide citation)

A film for releasing at least one of an anti-microbial agent, oxygen, and a medicament includes a flexible, porous layer (18) such as a woven, non-woven, or knitted cloth or a layer of open cell foam. A first dry reagent (12) and a second dry reagent (14) which react in the presence of a dilutant to ...


9
Paul S Malchesky: Microbial decontamination system with components porous to anti-microbial fluids. Steris Corporation, Fay Sharpe Beall Fagan Minnich & McKee, September 3, 1996: US05552115 (36 worldwide citation)

A countertop decontamination unit (A) has a decontamination chamber (10) for receiving a tray or module (C) which contains items to be sterilized, disinfected, or otherwise microbially decontaminated. The tray or walls of the decontamination chamber itself provide fluid outlets from which an anti-mi ...


10
Maciej Zborowski, Paul S Malchesky: Magnetic field separation and analysis system. Cleveland Clinic Foundation, Fay Sharpe Beall Fagan Minnich & McKee, October 1, 1991: US05053344 (36 worldwide citation)

A magnetic field separation system includes a magnet unit having first and second pole members forming a linear gap with a relatively high magnetic field density therebetween. A flow chamber comprised of first and second optically transparent slides mounted so as to define a generally planar fluid p ...