1
James M Griffith, Mario Maciel, Walter L Henry, Paul J Zalesky: Ultra-thin acoustic transducer and balloon catheter using same in imaging array subassembly. Inter Therapy, Nixon & Vanderhye, June 27, 1989: US04841977 (312 worldwide citation)

An array of miniature ultrasound crystals mounted on preassembled subassembly which is, in turn, mounted on a small lumen catheter provides dimensional and other quantitative information relating to arterial wall geometry and character at disease or obstruction sites. Balloons also mounted to the ca ...


2
James M Griffith, Paul J Zalesky, James M Gessert, Viet P Dinh, James D Passafaro: Intravascular ultrasonic imaging probe and methods of using same. InterTherapy, Nixon & Vanderhye, May 26, 1992: US05115814 (168 worldwide citation)

An intravascular ultrasonic imaging probe includes a transducer subassembly adapted to being rotated within a guide catheter via a drive cable. The guide catheter establishes a bearing surface for supporting the transducer subassembly during rotation while also mechanically isolating the rotating tr ...


3
Joe F Guess, Paul J Zalesky: Intravascular ultrasonic angioplasty probe. Inter Therapy, Nixon & Vanderhye, December 3, 1991: US05069664 (148 worldwide citation)

A probe for ultrasonically removing unwanted biological material, for example, from a vessel in a patient's cardiovascular system, includes a catheter assembly having distal and proximal catheter sections, each defining a respective lumen. A subassembly is connected to and between these catheter sec ...


4
Vincent Divino Jr, Seth A Foerster, James M Gessert, Robert A Mest, Paul J Zalesky: Apparatus for the preparation and delivery of gas-enriched fluids. TherOx, Margaret A Kivinski, September 24, 2002: US06454997 (113 worldwide citation)

A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that re ...


5
Vincent Divino Jr, Seth A Foerster, James M Gessert, Robert A Mest, Paul J Zalesky, James Richard Spears: Method for the preparation and delivery of gas-enriched fluids. TherOx, Fletcher Yoder & Van Someren, January 30, 2001: US06180059 (89 worldwide citation)

A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that re ...


6
J Richard Spears, Philip S Levin, Paul J Zalesky: High pressure perfusion device. Therox, Wayne State University, Pennie & Edmonds, August 25, 1998: US05797876 (75 worldwide citation)

The present invention includes a guidewire device capable of delivering perfusion fluids to a vascular site while at the same time exhibiting handling characteristics associated with existing non-perfusion guidewires. Preferred embodiments include a perfusion guidewire which closely matches the dime ...


7
Vincent Divino Jr, Seth A Foerster, James M Gessert, Robert A Mest, Paul J Zalesky, James Richard Spears: Method for the preparation and delivery of gas-enriched fluids. TherOx, Wayne State University, Margaret A Kivinski, January 13, 2004: US06676900 (66 worldwide citation)

A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that re ...


8
Vincent Divino Jr, Paul J Zalesky, William R Patterson: Method for blood oxygenation. TherOx, Margaret A Kivinski, July 22, 2003: US06596235 (66 worldwide citation)

An apparatus and method for blood oxygenation is provided, advantageously comprising an extracorporeal circuit for the preparation and delivery of hyperoxic or hyperbaric blood. In one embodiment, an apparatus for gas-supersaturating fluids, e.g., physiologic saline, includes a chamber having a firs ...


9
J Richard Spears, Philip S Levin, Paul J Zalesky, Vincent Divino Jr: High pressure transluminal fluid delivery device. TherOx, Pennie & Edmonds, September 28, 1999: US05957899 (65 worldwide citation)

The present invention includes a fluid delivery device capable of delivering perfusion or other fluids to a vascular site. Preferred embodiments permit delivery of large quantities of fluid without causing recoil of the device, and without causing trauma to the vascular site.


10
J Richard Spears, Philip S Levin, Paul J Zalesky, Vincent Divino Jr: Angioscopy apparatus and methods. Therox, Wayne State University, Fletcher Yoder & Van Someren, September 26, 2000: US06123698 (62 worldwide citation)

The present invention includes a fluid delivery device capable of delivering perfusion or other fluids to a vascular site. Preferred embodiments permit delivery of large quantities of fluid without causing recoil of the device, and without causing trauma to the vascular site.