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Paul C Harris, Curtis C Genstler: Automated patient sample analysis instrument. March 17, 1992: US05096670 (87 worldwide citation)

An automated sample analysis instrument positively identifies and maintains the identity of a plurality of patient samples contained in individual sample containers. The invention prevents sample misidentification, especially when patient sample must be transferred from one sample container to react ...


2
Linda K Cragle, Paul C Harris, Shih Yun Lee, Ker Kong Tung, Morton A Vodian: Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect. Beckman Instruments, W H May, A Grant, R S Friedman, June 17, 1986: US04595661 (70 worldwide citation)

An immunoassay for assaying an antigenic substance (Ag) in a fluid. The immunoassay is the type which comprises contacting the fluid with at least one first entity selected from a group consisting of an antibody (Ab) to the Ag, a soluble, labeled antibody (L-Ab.sub.a) to the Ag, and an antibody (Ab. ...


3
Philip M Clegg, Paul C Harris, Curtis C Genstler: Real time three-dimensional machine locating system. December 19, 1995: US05477459 (67 worldwide citation)

A method and system for locating the point P.sub.0 which defines the location of a machine, e.g. an earth moving machine, a surveying or locating machine, etc., in relation to a tract or area of interest by measuring the angles defined by two different sets of reference points selected from at least ...


4
Donald Elliott Brooks, Paul C Harris, Andrew D Olal, Zongcen Charles Xie, Brian G Richards: Compensation for non-specific signals in quantitative immunoassays. Response Biomedical, Hamilton Brook Smith & Reynolds P C, January 21, 2003: US06509196 (31 worldwide citation)

Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample are disclosed. The methods involve providing a membrane having an application point, a detection zone, and a contact region, where the contact region is between the application point and the detection zone, a ...


5
Marnix L Bosch, Paul C Harris, Steven J Monahan, Allen Turner, Alton L Boynton, Patricia A Lodge: Tangential flow filtration devices and methods for leukocyte enrichment. Northwest Biotherapeutics, Townsend and Townsend and Crew, April 13, 2010: US07695627 (22 worldwide citation)

The present invention provides tangential flow filtration devices and methods for enriching a heterogeneous mixture of blood constituents for leukocytes by removal of non-leukocyte blood constituents. In one particular embodiment the device can provide a composition enriched in monocytes. One embodi ...


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Paul C Harris, Linda J Stone: Apparatus and method using a new reaction capsule. Beckman Instruments, William H May, Arnold Grant, Gary T Hampson, October 3, 1989: US04871683 (20 worldwide citation)

A system and method for performing a clinical assay, both including the use of a reaction capsule having a hydrophobic membrane which may be repeatedly wetted and rendered hydrophobic. A pressure differential across the membrane causes liquid flow therethrough to be initiated and the hydrophobic sta ...


8
Paul C Harris, Curtis C Genstler: Automated patient sample analysis instrument having tubes and reaction wells washing apparatus. Pasteur Sanofi Diagnostics, Fredrikson & Byron PA, July 22, 1997: US05650122 (19 worldwide citation)

An automated sample analysis instrument positively identifies and maintains the identity of a plurality of patient samples contained in individual sample containers. The invention prevents sample misidentification, especially when patient sample must be transferred from one sample container to react ...


9
Linda K Cragle, Paul C Harris, Shih Yun Lee, Ker Kong Tung, Morton A Vodian: Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations. Beckman Instruments, W H May, A Grant, R S Frieman, May 20, 1986: US04590169 (19 worldwide citation)

A direct particle agglutination immunoassay for assaying an antigenic substance (Ag) in a fluid. The immunoassay is the type which comprises:


10
Paul C Harris, Chan S Oh: Bidentate conjugate and method of use thereof. Beckman Instruments, William H May, Arnold Grant, Richard P Burgoon Jr, March 23, 1993: US05196351 (18 worldwide citation)

A novel bidentate conjugate has two different chemical moieties, or bidentate members, attached through an adequate spacer moiety. Each bidentate member acts as a small molecule ligand and is capable of specifically binding to a different macromolecular substance. The bidentate members are relativel ...