1
Oshlack Benjamin, Chasin Mark: Orally administrable opioid formulations having extended duration of effect.. Euro Celtique, April 12, 1995: EP0647448-A1 (161 worldwide citation)

Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains a plurality of substrates includin ...


2
Oshlack Benjamin: Controlled release bases for pharmaceuticals.. Euro Celtique, January 20, 1988: EP0253104-A1 (105 worldwide citation)

The release of therapeutically active agents from controlled release bases is extended by using a combination of a higher aliphatic alcohol and an acrylic resin as the base material.


3
Heafield Joanne, Knott Trevor John, Leslie Stewart Thomas, Malkowska Sandra Therese A, Miller Ronald Brown, Prater Derek Allan, Smith Kevin John, Chasin Mark, Goldenheim Paul, Oshlack Benjamin, Pedi Frank Jr, Sackler Richard, Kaiko Robert: Sustained release compositions containing morphine.. Euro Celtique, February 1, 1995: EP0636370-A1 (89 worldwide citation)

In order to provide a sustained release pharmaceutical formulation containing morphine which is suitable for administration on a once daily basis, in a first aspect, an orally administrable sustained release dosage unit form contains morphine, or a pharmaceutically acceptable salt thereof, as active ...


4
Oshlack Benjamin, Pedi Frank, Chasin Mark: Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer.. Euro Celtique, June 30, 1993: EP0548448-A1 (77 worldwide citation)

A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and rel ...


5
Sackler Richard, Oshlack Benjamin, Goldenheim Paul, Chasin Mark, Kaiko Robert, Pedi Frank: Opioid formulations having extended controlled release.. Euro Celtique, January 4, 1995: EP0631781-A1 (60 worldwide citation)

Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24 hours, have a dissolution rate in-vitro of the dosage form, when measured by the USP Paddle Method of 100 rp ...


6
Oshlack Benjamin, Chasin Mark, Pedi Frank Jr: Stabilized controlled release formulations having acrylic polymer coating.. Euro Celtique, August 4, 1993: EP0553392-A1 (54 worldwide citation)

A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of an acrylic polymer is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of the plasticized acrylic polymer and then curing the coated substrate at ...


7
Oshlack Benjamin, Huang Hua Pin: Tamper resistant dosage form comprising co-extruded, adverse agent particles and process of making same. Euro Celtique, Oshlack Benjamin, Huang Hua Pin, MARKEY James G, November 4, 2004: WO/2004/093819 (33 worldwide citation)

The present invention relates to co-extruded pharmaceutical compositions and dosage forms comprising an adverse agent, such as an opioid antagonist, which can be sequestered. The pharmaceutical compositions and dosage forms diversion of a dosage form containing an active pharmaceutical agent, such a ...


8
Oshlack Benjamin, Van, Buskirk Glen, Chasin Mark, Huang Hua Pin, Vashi Vijay: Pharmaceutical products. Euro Celtique, Oshlack Benjamin, Van, Buskirk Glen, Chasin Mark, Huang Hua Pin, Vashi Vijay, DAVIDSON Clifford M, November 4, 2004: WO/2004/093801 (30 worldwide citation)

Disclosed in certain embodiments is a dosage form comprising a plurality of extruded particles comprising an adverse agent or antagonist and a layer disposed about the particles.


9
Oshlack Benjamin, Chasin Mark: Orally administrable opioid formulations having extended duration of effect. Euro Celtique, August 4, 2004: EP1442745-A1 (26 worldwide citation)

Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains a plurality of substrates includin ...


10
Oshlack Benjamin, Chasin Mark, Huang Hua Pin, Sackler David: Melt-extruded orally administrable opioid formulations. Euro Celtique, October 1, 2003: EP1348429-A2 (25 worldwide citation)

Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed. Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrus ...