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Sun Ying, Niu Deqiang, Xu Guoyou, Or Yat Sun, Wang Zhe: Macrocyclic oximyl hepatitis c protease inhibitors. Enanta Pharmaceuticals, Sun Ying, Niu Deqiang, Xu Guoyou, Or Yat Sun, Wang Zhe, NAKAJIMA Suanne, December 13, 2007: WO/2007/143694 (52 worldwide citation)

The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere wi ...


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Niu Deqiang, Gai Yonghua, Or Yat Sun, Wang Zhe: Arylalkoxyl hepatitis c virus protease inhibitors. Enanta Pharmaceuticals, Niu Deqiang, Gai Yonghua, Or Yat Sun, Wang Zhe, NAKAJIMA Suanne, February 21, 2008: WO/2008/022006 (46 worldwide citation)

The present invention discloses compounds of Formula I or II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interf ...


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Sun Ying, Niu Deqiang, Or Yat Sun, Wang Zhe: Triazolyl macrocyclic hepatitis c serine protease inhibitors. Enanta Pharmaceuticals, Sun Ying, Niu Deqiang, Or Yat Sun, Wang Zhe, ELMORE Carolyn S, February 21, 2008: WO/2008/021960 (45 worldwide citation)

The present invention relates to compounds of Formula I or II, or pharmaceutically acceptable salts, esters or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interf ...


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Niu Deqiang, Moore Joel, Liu Dong, Gai Yonghua, Chen Zhigang, Or Yat Sun, Wang Zhe: Acylaminoheteroaryl hepatitis c virus protease inhibitors. Enanta Pharmaceuticals, Niu Deqiang, Moore Joel, Liu Dong, Gai Yonghua, Chen Zhigang, Or Yat Sun, Wang Zhe, SUANNE Nakajima, February 21, 2008: WO/2008/021956 (40 worldwide citation)

The present invention discloses compounds of formulae (I) and (II), or pharmaceutically acceptable salts, esters, or prodrugs thereof: Which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention ...


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Or Yat Sun, Moore Joel D, Liu Dong, Sun Ying, Gai Yonghua, Tang Datong, Niu Deqiang, Xu Guoyou, Wang Zhe: Quinoxalinyl macrocyclic hepatitis c virus serine protease inhibitors. Enanta Pharmaceuticals, Or Yat Sun, Moore Joel D, Liu Dong, Sun Ying, Gai Yonghua, Tang Datong, Niu Deqiang, Xu Guoyou, Wang Zhe, SUANNE Nakajima, January 3, 2008: WO/2008/002924 (40 worldwide citation)

The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof, which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present ...


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Niu Deqiang, Or Yat Sun, Wang Zhe: Aza-tripeptide hepatitis c serine protease inhibitors. Enanta Pharmaceuticals, Niu Deqiang, Or Yat Sun, Wang Zhe, ELMORE Carolyn S, November 6, 2008: WO/2008/134397 (37 worldwide citation)

The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere w ...


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LEE Kwangho, NIU Deqiang, PETTER Russell C, SINGH Juswinder: COMPOSÉS HÉTÉROARYLE ET LEURS UTILISATIONS, HETEROARYL COMPOUNDS AND USES THEREOF. AVILA THERAPEUTICS, LEE Kwangho, NIU Deqiang, PETTER Russell C, SINGH Juswinder, BUTEAU Kristen C, May 10, 2012: WO/2012/061303 (33 worldwide citation)

Heterocyclic pynmidine compounds that modulate mutant-selective epidermal growth factor receptor (EGFR) kinase activity are disclosed. Selectivity in modulation of various EGFR mutant activity has been disclosed. Pharmaceutical compositions comprising the pynmidine derivative, and methods of treatme ...


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