1
Rodolfo A Morales, Niel F Starksen: Devices and methods for heart valve repair. Guided Delivery Systems, Morrison & Foerster, January 17, 2006: US06986775 (378 worldwide citation)

Methods and devices provide constriction of a heart valve annulus to treat cardiac valve regurgitation and other conditions. Embodiments typically include a device for attaching a cinching or tightening apparatus to a heart valve annulus to reduce the circumference of the annulus, thus reducing valv ...


2
Niel F Starksen, John To, Rodolfo A Morales: Methods for remodeling cardiac tissue. Guided Delivery Systems, Morrison & Foerster, September 15, 2009: US07588582 (107 worldwide citation)

Described herein are methods of remodeling the base of a ventricle. In particular, methods of remodeling a valve annulus by forming a new fibrous annulus are described. These methods may result in a remodeled annulus that corrects valve leaflet function without substantially inhibiting the mobility ...


3
Niel F Starksen, Karl S Im, Mariel Fabro, Stephen C Meier, Eugene Serina: Methods and devices for catheter advancement and delivery of substances therethrough. Guided Delivery Systems, Morrison & Foerster, March 5, 2013: US08388680 (103 worldwide citation)

Methods and devices for successively advancing a plurality of catheters over a guide element to a body tissue are described. In some of the methods, the guide element may be attached to the body tissue, which may be accessible minimally invasively. In certain variations, the guide element may not be ...


4
Niel F Starksen, Nick Pliam, Rodolfo A Morales, John To: Cardiac visualization devices and methods. Guided Delivery Systems, Morrison & Foerster, May 19, 2009: US07534204 (66 worldwide citation)

Devices and methods for facilitating transvascular, minimally invasive and other “less invasive” surgical procedures generally include a sheath with an expandable balloon at the distal end, an inflation lumen for expanding the balloon, and a device passage lumen for allowing passage of one or more s ...


5
Niel F Starksen: Devices and methods for cardiac annulus stabilization and treatment. Guided Delivery Systems, Morrison & Foerster, July 13, 2010: US07753922 (59 worldwide citation)

Devices and methods generally provide enhanced stabilization, exposure and/or treatment of a cardiac valve annulus. Methods generally involve introducing a stabilizing member beneath one or more leaflets of a heart valve to engage the annulus at an intersection between the leaflets and the interior ...


6
Niel F Starksen, John To, Mariel Fabro, Michael F Wei, Rodolfo A Morales: Delivery devices and methods for heart valve repair. Guided Delivery Sytems, Morrison & Foerster, February 23, 2010: US07666193 (54 worldwide citation)

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contac ...


7
Niel F Starksen, John To, Mariel Fabro, Michael F Wei, Rodolfo A Morales: Delivery devices and methods for heart valve repair. Guided Delivery Systems, Morrison & Foerster, July 13, 2010: US07753924 (41 worldwide citation)

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contac ...


8
Niel F Starksen: Apparatus and method for implanting electrical leads in the heart. Townsend and Townsend and Crew, November 5, 1996: US05571161 (41 worldwide citation)

A steerable guide catheter for the placement of electrical lead wires useful for cardiac pacemakers and other electrophysiology devices includes an atraumatic balloon at its distal end. The catheter has a proximal hemostatic seal and is axially splittable so that it may be removed over an electrical ...


9
John To, Niel F Starksen, Tenny C Calhoun: Methods and devices for termination. Guided Delivery Systems, Morrison & Foerster, February 8, 2011: US07883538 (37 worldwide citation)

Devices and methods used in termination of a tissue tightening procedure are described. Termination includes the cinching of a tether to tighten the tissue, locking the tether to maintain tension, and cutting excess tether. In procedures involving anchors secured to the tissue, the tether is coupled ...


10
Niel F Starksen, John To, Rodolfo A Morales: Delivery devices and methods for heart valve repair. Guided Delivery Systems, Morrison & Foerster, July 20, 2010: US07758637 (37 worldwide citation)

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contac ...