1
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Methods and apparatus for thermally-induced renal neuromodulation. Ardian, Perkins Coie, November 10, 2009: US07617005 (323 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...


2
Denise Demarais, Benjamin J Clark, Nicolas Zadno, Erik Thai, Hanson Gifford III: Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach. Ardian, Perkins Coie, November 17, 2009: US07620451 (305 worldwide citation)

Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other c ...


3
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Methods and apparatus for thermally-induced renal neuromodulation. Ardian, Perkins Coie, May 18, 2010: US07717948 (301 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...


4
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai: Methods and apparatus for intravascularly-induced neuromodulation. Ardian, Perkins Coie, July 13, 2010: US07756583 (257 worldwide citation)

Methods and apparatus are provided for intravascularly-induced neuromodulation using a pulsed electric field, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation, etc., in target n ...


5
Denise Demarals, Hanson Gifford III, Mark Deem, Howard R Levin, Mark Gelfand, Nicolas Zadno: Methods and apparatus for monopolar renal neuromodulation. Ardian, Perkins Coie, March 6, 2012: US08131371 (248 worldwide citation)

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or bl ...


6
Denise Demarais, Nicolas Zadno: Methods and apparatus for inducing controlled renal neuromodulation. Ardian, Perkins Coie, May 3, 2011: US07937143 (159 worldwide citation)

Methods and apparatus are provided for inducing, monitoring and controlling renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. In some embodiments, tissue impedance, conductance or conductivity may be monitored to determine the effects of pulsed elect ...


7
Denise Demarais, Benjamin J Clark, Nicolas Zadno, Erik Thai, Hanson Gifford III: Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach. Ardian, Perkins Coie, January 18, 2011: US07873417 (149 worldwide citation)

Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other c ...


8
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, January 8, 2013: US08347891 (131 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...


9
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, June 4, 2013: US08454594 (102 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...


10
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Ultrasound apparatuses for thermally-induced renal neuromodulation. Medtronic Ardian Luxembourg r l, September 30, 2014: US08845629 (19 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...



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