1
Nicholas Abbott, Pieter Stroeve, Timothy B Dubrovsky, Zhizhong Hou: Support for high performance affinity chromatography and other uses. The Regents of the University of California, Townsend and Townsend and Crew, August 21, 2001: US06277489 (167 worldwide citation)

Multilayered particulate materials are formed by coating a particulate substrate with a metal and adsorbing an organic layer comprising a recognition moiety onto the metal film. The recognition moiety interacts with an analyte of interest allowing for its detection, purification, etc. Suitable recog ...


2
Zhizhong Hou, Pieter Stroeve, Nicholas Abbott: Controllable ion-exchange membranes. The Regents of the University of California, Townsend and Townsend and Crew, October 22, 2002: US06468657 (88 worldwide citation)

Multilayered porous materials are formed by coating a porous substrate with a metal and adsorbing an organic layer comprising a recognition moiety onto the metal film. The recognition moiety interacts with an analyte of interest allowing for its detection, purification, etc. Suitable recognition moi ...


3
Craig Jon Hawker, James Lupton Hedrick, Nicholas Abbott: Substrates prepared by chemical amplification of self-assembled monolayers with spatially localized polymer brushes. International Business Machines Corporation, The Regents of the University of California, Dianne E Reed, Mark L Warzel, Reed & Eberle, August 24, 2004: US06780492 (59 worldwide citation)

A method is disclosed for providing a patterned surface wherein predetermined regions of the surface are masked with a self-assembled monolayer (“SAM”) covalently bound to a brush polymer overlayer. The remainder of the substrate surface will generally be functionalized with a second self-assembled ...


4
Christopher Murphy, Barbara Israel, Nicholas Abbott: Substrates, devices, and methods for cellular assays. Platypus Technologies, Medlen & Carroll, March 28, 2006: US07018838 (39 worldwide citation)

The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sa ...


5
Craig Jon Hawker, James Lupton Hedrick, Nicholas Abbott: Method for forming polymer brush pattern on a substrate surface. International Business Machines Corporation, Reed & Associates, July 2, 2002: US06413587 (32 worldwide citation)

A method is disclosed for providing a patterned surface wherein predetermined regions of the surface are masked with a self-assembled monolayer (“SAM”) covalently bound to a brush polymer overlayer. The remainder of the substrate surface will generally be functionalized with a second self-assembled ...


6
Christopher Murphy, Barbara Israel, Nicholas Abbott: Substrates, devices, and methods for cellular assays. Platypus Technologies, Casimir Jones s c, November 30, 2010: US07842499 (5 worldwide citation)

The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provide ...


7
Nicholas Abbott, Christopher Murphy, Barbara Israel: Substrates, devices, and methods for quantitative liquid crystal assays. Platypus Technologies, Casimir Jones S C, February 23, 2010: US07666661 (5 worldwide citation)

The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sa ...


8
Bharat Acharya, Avijit Sen, Nicholas Abbott, Kurt Kupcho: Detection of vapor phase compounds by changes in physical properties of a liquid crystal. Platypus Technologies, Casimir Jones S C, May 15, 2012: US08178355 (4 worldwide citation)

The present invention relates to the field of detection of components in gas phase, and in particular to detection of nitric oxide exhaled as a component of breath, using a liquid crystal assay format and a device utilizing liquid crystals as part of a reporting system.


9
Nicholas Abbott, Christopher Murphy, Barbara Israel: Compositions and liquid crystals. Platypus Technologies, Casimir Jones S C, February 16, 2010: US07662572 (4 worldwide citation)

The present invention relates to compounds, compositions, and methods in the field of detection of analytes. In particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic mol ...


10
Nicholas Abbott, Christopher Murphy, Barbara Israel, Doug Hansmann: Bead based assays using a liquid crystal reporter. Platypus Technologies, Casimir Jones S C, May 12, 2009: US07531366 (4 worldwide citation)

The present invention relates to the field of detection of analytes, and in particular to detection of viruses, cells, bacteria, lipid-membrane containing organisms, proteins, nucleic acids, carbohydrates and other biomolecules, organic molecules and inorganic molecules using a liquid crystal assay ...