1
Ni Ding, Michael N Helmus: Drug release stent coating process. Schneider, Pennie & Edmonds, November 17, 1998: US05837313 (777 worldwide citation)

A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologi ...


2
Ni Ding, Michael N Helmus: Drug coating with topcoat. Schneider, Pennie & Edmonds, August 8, 2000: US06099562 (693 worldwide citation)

A coating and method for a coating an implantable device or prostheses are disclosed. The coating includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein. The coating further includes a topcoat which covers less than t ...


3
Ni Ding, Michael N Helmus: Medical devices with long term non-thrombogenic coatings. Schneider, September 19, 2000: US06120536 (690 worldwide citation)

A coating and method for implantable open lattice metallic stent prostheses are disclosed. The coating includes a relatively thin layer of biostable elastomeric material containing an amount of biologically active material, particularly heparin, dispersed in the coating in combination with a non-thr ...


4
Ni Ding: Method of applying drug-release coatings. Schneider, Pennie & Edmonds, November 9, 1999: US05980972 (527 worldwide citation)

The invention is directed to a method of applying drug-release coatings whereby a polymer can be dissolved in a first solvent (solvent A) to form a polymer system and a drug can be dissolved or suspended in a second solvent (solvent B) to form a drug system. The coating or layer of coating so formed ...


5
Ni Ding, Michael N Helmus: Drug release stent coating. Boston Scientific Corporation, March 19, 2002: US06358556 (461 worldwide citation)

A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologi ...


6
Fritz Hostettler, David Rhum, Michael R Forman, Michael N Helmus, Ni Ding: Medical device coated with interpenetrating network of hydrogel polymers. Schneider, Vidas Arrett & Steinkraus, September 19, 2000: US06120904 (453 worldwide citation)

A medical device comprising an organic polymer substrate material having a coating thereon, the coating comprising an interpenetrating network of two different hydrogel polymers, one of which is a polyurethane/polyurea hydrogel polymer, the polyurethane/polyurea hydrogel polymer being linked to the ...


7
Ni Ding, Jennifer E Raeder Devens, Tuyethoa Thi Trinh: Drug-releasing coatings for medical devices. Schneider, Pennie & Edmonds, March 28, 2000: US06042875 (424 worldwide citation)

The invention is directed to medical devices having a drug-releasing coating and methods for making such coated devices. The coating permits timed or prolonged pharmacological activity on the surface of medical devices through a reservoir concept. Specifically, the coating comprises at least two lay ...


8
Fritz Hostettler, David Rhum, Michael R Forman, Michael N Helmus, Ni Ding: Process for preparation of slippery, tenaciously adhering, hydrophilic polyurethane hydrogel coating, coated polymer and metal substrate materials, and coated medical devices. Schneider, Vidas Arrett & Steinkraus, June 27, 2000: US06080488 (378 worldwide citation)

A process for the preparation of slippery, hydrophilic polyurethane hydrogel coating compositions, and materials composed of a polymeric plastic or rubber substrate or a metal substrate with a coating of a slippery, hydrophilic polyurethane hydrogel thereon, such that the coating composition tenacio ...


9
Ni Ding, Michael N Helmus: Drug coating with topcoat. Schneider, September 4, 2001: US06284305 (296 worldwide citation)

A coating and method for a coating an implantable device or prostheses are disclosed. The coating includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein. The coating further includes a topcoat which covers less than t ...


10
Ni Ding, W Scott Andrus: Medical device with sponge coating for controlled drug release. Boston Scientific Corporation, April 2, 2002: US06364856 (258 worldwide citation)

The medical devices of the invention comprise an expandable portion which is covered with a sponge coating for release of at least one biologically active material. The sponge coating is made of a non-hydrogel polymer having a plurality of voids. The device can further include means for infusing or ...