Baker Geoffrey Harold, Beeley Lee James, Newsome Peter Martin, Richards David Hugh: Imidazoline derivatives.. Beecham Group, January 19, 1983: EP0070084-A2 (12 worldwide citation)

Compounds of formula (I): wherein R is halogen, alkyl or alkoxy; R is hydrogen, halogen, alkyl or alkoxy; R is an optionally substituted, saturated, unsaturated or aromatic, carbo- or hetero-, mono- or bi-cyclic group; R is hydrogen or alkyl, -@@ (CH2)n - R is located meta or para to the imidazoliny ...

Newsome Peter Martin, Mullen Noel Austin: Anti-diarrhoea veterinary composition.. Beecham Group, March 18, 1981: EP0025269-A1 (10 worldwide citation)

Vasoconstrictor alpha -adrenergic agonists of formula (I) A-B-C (1) wherein, A is a 2-imidazoline group or a guanidine group; B is a chemical bond or a linking group one or two atoms in length; and C is a C6-10 mono- or bi-cyclic group which is either an aromatic group, a heteroaromatic group contai ...


Bywater Robert James, Newsome Peter Martin: Treatment of diarrhoea.. Beecham Group, November 28, 1984: EP0126343-A1 (7 worldwide citation)

A compound of formula (I) wherein (i) P is a bond, oxygen, sulphur, NR, methylene, ethylene or vinylene and X is and R and R are each hydrogen, halogen, hydroxy, acyloxy, lower alkyl, lower alkoxy or trifluoromethyl and R is hydrogen, lower alkyl, lower aralkyl; aminoethyl or aminopropyl each option ...


Newsome Peter Martin: Pharmaceutical or veterinary compositions containing guanoxabenz.. Beecham Group, June 27, 1984: EP0112061-A2 (3 worldwide citation)

A pharmaceutical or veterinary oral rehydration composition for treating diarrhoea or scours comprises guanoxabenz or an acid addition salt thereof, in aqueous solution also containing at least 0.5% w/v of an actively absorbed monosaccharide, at least 25mM sodium ions and having an osmolarity of les ...

Newsome Peter Martin, Burgess Malcolm Neil, Richards David Hugh, Mullen Noel Austin: Treatment of diarrhoea.. Beecham Group, September 1, 1982: EP0059057-A1 (2 worldwide citation)

alpha 2-adrenergic agonists, especially compounds (I) wherein R is hydrogen or hydroxy R is hydrogen or methyl R is hydrogen or methyl R is hydrogen, meta-hydroxy or orth-methoxy and R is hydrogen, para-hydroxy or meta-methoxy and salts thereof may be administered orally for treatment of diarrhoea a ...

Newsome Peter Martin, Moss Stephen Frederick: Novel compounds.. Beecham Group, July 24, 1985: EP0149140-A2 (2 worldwide citation)

Compounds of formula (I) wherein R is halogen, C1-4 alkyl or C1-4 alkoxy; R is hydrogen, C1-4 alkyl or optionally substituted aryl; R and R are the same or different and each is hydrogen, C1-6 alkyl, optionally substituted aryl or optionally substituted aralkyl; R is hydrogen, halogen, C1-4 alkyl or ...

Newsome Peter Martin, Beeley Lee James, Moss Stephen Frederick, Bywater Robert James: Treatment of diarrhoea.. Beecham Group, September 11, 1985: EP0154298-A2 (1 worldwide citation)

A method for treatment or preventing diarrhoea or scours which comprises administering to a human or non-human animal in need thereof an effective non toxic amount of a compound of formula (I); or an N-oxide or pharmaceutically acceptable quaternised derivative or pharmaceutically acceptable salt th ...