1
Stéphane De Lombaert
DE LOMBAERT Stéphane, LIU Weimin, LO Ho Yin, NEMOTO Peter Allen: INHIBITEURS BENZIMIDAZOLE DE PRODUCTION DE LEUCOTRIÈNES, BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, DE LOMBAERT Stéphane, LIU Weimin, LO Ho Yin, NEMOTO Peter Allen, MORRIS Michael P, May 10, 2012: WO/2012/061169 (1 worldwide citation)

The present invention relates to compounds of formula (IA), (IB) and (IC) and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of var ...


2
Cywin Charles, Pullen Steven S, Roth Gregory Paul, Snow Roger John, Fleck Roman Wolfgang, Takahashi Hidenori, Winters Michael, Qiao Lei, Nemoto Peter Allen, Moriarity Kevin J, Wang Ji, Bentzien Joerg, Cook Brian, Lo Ho Yin: Substituted benzimidazole compounds. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert P, February 19, 2004: WO/2004/014905 (8 worldwide citation)

Disclosed are substituted benzimidazole compounds of formula (I) wherein R¿1?, R¿2?, R¿3?, R¿4? and X¿a? are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders an ...


3

4

5

6
Kosley Raymond W Jr, Flanagan Denise M, Martin Lawrence Leo, Nemoto Peter Allen: (amino)Acetamides and related (1h-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, October 6, 1993: EP0563916-A1 (4 worldwide citation)

There are disclosed compounds having the formula wherein X is hydrogen, chloro, bromo, fluoro, hydroxy, loweralkoxy, arylloweralkoxy, acyloxy, loweralkylaminocarbonyloxy, diloweralkylaminocarbonyloxy, amino, loweralkylamino, diloweralkylamino, acylamino, loweralkyl or trifluoromethyl; Y is hydrogen, ...


7

8
Wettlaufer David Gordon, Shutske Gregory Michael, Nemoto Peter Allen: 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, March 11, 1992: EP0474012-A1 (3 worldwide citation)

This invention relates to 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5H)-ones and -ols of the formula wherein X is or loweralkyl; Y is hydrogen, halogen, loweralkyl, loweralkoxy, trifluoromethyl, nitro or amino; R is H when the bond between the oxygen atom and the carbon atom in question is a single bo ...


9
Effland Richard Charles, Davis Larry, Olsen Gordon Edward, Klein Joseph Thomas, Wettlaufer David Gordon, Nemoto Peter Allen: 1-(substituted pyridinylamino)-1h-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments.. Hoechst Marion Roussel, January 29, 1992: EP0468401-A2 (2 worldwide citation)

There are disclosed various compounds of the formula below, where n is 0 or 1; X is hydrogen, halogen, nitro, amino, trifluoromethyl, loweralkyl, or loweralkoxy; Y is hydrogen, halogen, nitro, amino, trifluoromethyl, loweralkyl, or loweralkoxy; R1 is hydrogen, loweralkyl, arylloweralkyl, loweralkeny ...


10
Wettlaufer David Dr, Nemoto Peter Allen: (Pyrrolidinyl)Phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments.. Hoechst Roussel Pharma, September 13, 1995: EP0671388-A1 (1 worldwide citation)

Novel (pyrrolidinyl)phenyl carbamates and related compounds, intermediates and processes for the preparation thereof, and methods of relieving memory dysfunction utilizing the carbamates and related compounds, or compositions thereof are disclosed.